Positive control: SW1353 cell lysates.
This antibody detects an approximately 42 kDa band in SW1353 cell lysates by Western blot.
CD186, also known as CXCR6, is a G protein-coupled chemokine receptor reported to be one of the cellular receptors of HIV and SIV. CD186 is expressed by NKT cells, various subtypes of T cells with activated and memory phenotypes, and some plasma cells. It has been reported that mouse liver NK cells, but not naïve or splenic NK cells, express CD186. The ligand of CD186, CXCL16, is expressed by macrophages, dendritic cells and liver endothelial cells. Being highly expressed on NKT cells, CD186 is often used as a proxy marker of this cell subset.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 6; CC motif chemokine; CCmotif chemokine; CD186; CD186 antigen; CDw186; chemokine (C-X-C motif) receptor 6; CXC; CXC motif chemokine; CXC-R6; CXCR-6; G protein-coupled receptor; G-protein coupled receptor bonzo; G-protein coupled receptor STRL33; OTTHUMP00000209997; OTTHUMP00000209998
Gene Aliases: BONZO; CD186; CXCR6; STRL33; TYMSTR
UniProt ID: (Human) O00574
Entrez Gene ID: (Human) 10663