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CXCR6 (NT) Polyclonal Antibody
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Product Details
X1143P
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Antibody raised against a synthetic peptide corresponding to amino acids 11 to 25 of the human Bonzo protein. Peptide sequence differs from those of African green monkey and pig-tailed macaque by one or two amino acids, respectively.
Conjugate
Form
Liquid
Concentration
0.5-2 mg/mL
Amount
100 µg
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: Human spleen tissue lysates.
This antibody detects an approximately 45 kDa band in human spleen tissue lysate by Western blot.
Target Information
CD186, also known as CXCR6, is a G protein-coupled chemokine receptor reported to be one of the cellular receptors of HIV and SIV. CD186 is expressed by NKT cells, various subtypes of T cells with activated and memory phenotypes, and some plasma cells. It has been reported that mouse liver NK cells, but not naïve or splenic NK cells, express CD186. The ligand of CD186, CXCL16, is expressed by macrophages, dendritic cells and liver endothelial cells. Being highly expressed on NKT cells, CD186 is often used as a proxy marker of this cell subset.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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