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Proteintech
CXXC5 Polyclonal Antibody
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Product Details
16513-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CXXC5 Fusion Protein Ag9733 (96-322 aa encoded by BC017439)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Amount
28.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MMGGESADK ATAAAAAASL LANGHDLAAA MAVDKSNPTS KHKSGAVASL LSKAERATEL AAEGQLTLQQ FAQSTEMLKR VVQEHLPLMS EAGAGLPDME AVAGAEALNG QSDFPYLGAF PINPGLFIMT PAGVFLAESA LHMAGLAEYP MQGELASAIS SGKKKRKRCG MCAPCRRRIN CEQCSSCRNR KTGHQICKFR KCEELKKKPS AALEKVMLPT GAAFRWFQ (96-322 aa encoded by BC017439 )
Target Information
CXXC5 is zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development. CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitated the response of the stem cells to Wnt3a. Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CF5; CXXC finger 5 protein; CXXC-type zinc finger protein 5; Putative MAPK-activating protein PM08; Putative NF-kappa-B-activating protein 102; Retinoid-inducible nuclear factor; RINF; similar to Homo sapiens hypothetical protein (HSPC195)mRNA with GenBank Accession Number AF151029; unnamed protein product; WT1-induced Inhibitor of Dishevelled; zinc finger protein
Gene Aliases: 4930415K17Rik; CF5; CXXC5; HSPC195; RINF; TCCCIA00297; WID
UniProt ID: (Human) Q7LFL8, (Mouse) Q91WA4
Entrez Gene ID: (Human) 51523, (Mouse) 67393
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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