This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
PA5-29795 targets Cylindromatosis 1 in IF and WB applications and shows reactivity with Human samples.
The PA5-29795 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 243 of Human Cylindromatosis 1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Protein Aliases: BRSS; CDMT; CYLD1; CYLDI; cylindromatosis (turban tumor syndrome); Deubiquitinating enzyme CYLD; EAC; MFT; MFT1; probable ubiquitin carboxyl-terminal hydrolase CYLD; SBS; TEM; Ubiquitin carboxyl-terminal hydrolase CYLD; ubiquitin specific peptidase like 2; Ubiquitin thioesterase CYLD; ubiquitin thiolesterase CYLD; ubiquitin-specific-processing protease; Ubiquitin-specific-processing protease CYLD; USPL2
Gene Aliases: BRSS; CDMT; CYLD; CYLD1; CYLDI; EAC; HSPC057; KIAA0849; MFT; MFT1; SBS; TEM; USPL2
UniProt ID: (Human) Q9NQC7
Entrez Gene ID: (Human) 1540