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Immunogen sequence: SGGGSVSEN HMREKLYENG VTDSLKSNFA LLLKLSEELL DKWLSYPETQ HVPLSQHMLG FAMKSVTQMV MGSTFEDDQE VIRFQKNHGT VWSEIGKGFL DGSLDKNMTR KKQYEDALMQ LESVLRNIIK ERKGRNFSQH IFIDSLVQGN LNDQQILEDS MIFSLASCII TAKLCTWAIC FLTTSEEVQK KLYEEINQVF GNGPVTPEKI EQLRYCQHVL CETVRTAKLT PVSAQFQDIE GKIDRFIIPR ETLVLYALGV VLQDPNTWPS PHKFDPDRFD DELVMKTFSS LGFSGTQECP ELRFAYMVTT VLLSVLVKRL HLLSVEGQVI ETKYELVTSS REEAWITVSK RY (112-462 aa encoded by BC020616)
CYP20A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D, E)T, suggesting that its substrate may carry its own oxygen.
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Protein Aliases: Cytochrome P450 20A1; cytochrome P450 monooxygenase; cytochrome P450, 20a1; cytochrome P450, family 20, subfamily A, polypeptide 1
Gene Aliases: A930011N14Rik; CYP-M; CYP20A1; Cypm; UNQ667/PRO1301