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Proteintech

CYP20A1 Polyclonal Antibody

View all (7) CYP20A1 antibodies

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CYP20A1 Polyclonal Antibody

Product Details

16702-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:4,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500
-

Immunoprecipitation (IP)

0.5-4.0 µg
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CYP20A1 Fusion Protein Ag10099 (112-462 aa encoded by BC020616)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Amount

19.5 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: SGGGSVSEN HMREKLYENG VTDSLKSNFA LLLKLSEELL DKWLSYPETQ HVPLSQHMLG FAMKSVTQMV MGSTFEDDQE VIRFQKNHGT VWSEIGKGFL DGSLDKNMTR KKQYEDALMQ LESVLRNIIK ERKGRNFSQH IFIDSLVQGN LNDQQILEDS MIFSLASCII TAKLCTWAIC FLTTSEEVQK KLYEEINQVF GNGPVTPEKI EQLRYCQHVL CETVRTAKLT PVSAQFQDIE GKIDRFIIPR ETLVLYALGV VLQDPNTWPS PHKFDPDRFD DELVMKTFSS LGFSGTQECP ELRFAYMVTT VLLSVLVKRL HLLSVEGQVI ETKYELVTSS REEAWITVSK RY (112-462 aa encoded by BC020616)

Target Information

CYP20A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D, E)T, suggesting that its substrate may carry its own oxygen.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CYP-M; Cytochrome P450 20A1; cytochrome P450 monooxygenase; cytochrome P450, 20a1; cytochrome P450, family 20, subfamily A, polypeptide 1; unnamed protein product

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Gene Aliases: A930011N14Rik; CYP-M; CYP20A1; Cypm; UNQ667/PRO1301

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UniProt ID: (Human) Q6UW02, (Mouse) Q8BKE6, (Rat) Q6P7D4

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Entrez Gene ID: (Human) 57404, (Mouse) 77951, (Rat) 316435

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Function(s)
monooxygenase activity iron ion binding protein binding oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen heme binding metal ion binding fluorene oxygenase activity mono-butyltin dioxygenase activity tri-n-butyltin dioxygenase activity di-n-butyltin dioxygenase activity methylsilanetriol hydroxylase activity methyl tertiary butyl ether 3-monooxygenase activity 4-nitrocatechol 4-monooxygenase activity 4-chlorophenoxyacetate monooxygenase activity tert-butanol 2-monooxygenase activity alpha-pinene monooxygenase activity dimethylsilanediol hydroxylase activity ammonia monooxygenase activity hydroxymethylsilanetriol oxidase activity 2-hydroxyisobutyrate 3-monooxygenase activity alpha-pinene dehydrogenase activity bisphenol A hydroxylase B activity 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity 9-fluorenone-3,4-dioxygenase activity anthracene 9,10-dioxygenase activity 2-(methylthio)benzothiazole monooxygenase activity 2-hydroxybenzothiazole monooxygenase activity benzothiazole monooxygenase activity 2,6-dihydroxybenzothiazole monooxygenase activity pinacolone 5-monooxygenase activity thioacetamide S-oxygenase activity thioacetamide S-oxide S-oxygenase activity endosulfan monooxygenase I activity N-nitrodimethylamine hydroxylase activity 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity endosulfan ether monooxygenase activity pyrene 4,5-monooxygenase activity pyrene 1,2-monooxygenase activity 1-hydroxypyrene 6,7-monooxygenase activity 1-hydroxypyrene 7,8-monooxygenase activity phenylboronic acid monooxygenase activity spheroidene monooxygenase activity oxidoreductase oxygenase metabolite interconversion enzyme
Process(es)
oxidation-reduction process
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