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Invitrogen
CYP2F1 Polyclonal Antibody
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FIGURE: 1 / 2
CYP2F1 Antibody (PA5-96716) in IHC (P)
Immunohistochemistry analysis of CYP2F1 in paraffin-embedded mouse lung. Samples were incubated with CYP2F1 Polyclonal antibody (Product # PA5-96716) using a dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-96716
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 100-290 of human CYP2F1 (NP_0007652)
Conjugate
Form
Liquid
Concentration
1.11 mg/mL
Amount
111 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DYPAFFNFTK GNGIAFSSGD RWKVLRQFSI QILRNFGMGK RSIEERILEE GSFLLAELRK TEGEPFDPTF VLSRSVSNII CSVLFGSRFD YDDERLLTII RLINDNFQIM SSPWGELYDI FPSLLDWVPG PHQRIFQNFK CLRDLIAHSV HDHQASLDPR SPRDFIQCFL TKMAEEKEDP LSHFHMDTLL M; Positive Samples: SW620, BT-474, Mouse lung, Mouse liver, Rat liver, Rat brain; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Peripheral membrane protein
Target Information
CYP2F1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CYPIIF1; CYPIIF2; Cytochrome P450 2F1; Cytochrome P450 2F2; cytochrome P450, family 2, subfamily F, polypeptide 1; cytochrome P450, family 2, subfamily f, polypeptide 2; cytochrome P450, subfamily 2F, polypeptide 1; Cytochrome P450, subfamily IIF, polypeptide 1; Cytochrome P450-NAH-2; cytochrome P450IIF1; flavoprotein-linked monooxygenase; microsomal monooxygenase; Naphthalene dehydrogenase; Naphthalene hydroxylase; P450-NAH-2; unnamed protein product; xenobiotic monooxygenase
Gene Aliases: C2F1; CYP2F; CYP2F1; Cyp2f2; Cyp2f4; CYP4502F4; CYPIIF1
UniProt ID: (Human) P24903, (Rat) O35293
Entrez Gene ID: (Human) 1572, (Rat) 54246
monooxygenase activity
iron ion binding
arachidonic acid epoxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
oxygen binding
heme binding
metal ion binding
steroid hydroxylase activity
oxidoreductase
oxygenase
metabolite interconversion enzyme
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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