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Product Details
PA5-106814
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CYP39A1(Accession Q9NYL5), corresponding to amino acid residues L365-P415.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2854479
Product Specific Information
Antibody detects endogenous levels of total Cytochrome P450 39A1.
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 24-hydroxycholesterol 7-alpha-hydroxylase; Cytochrome P450 39A1; cytochrome P450, 39a1 (oxysterol 7alpha-hydroxylase); cytochrome P450, family 39, subfamily A, polypeptide 1; cytochrome P450, subfamily XXXIX (oxysterol 7 alpha-hydroxylase), polypeptide 1; hCYP39A1; mCYP39A1; Oxysterol 7-alpha-hydroxylase
Gene Aliases: CYP39A1; mCYP39A1
UniProt ID: (Human) Q9NYL5, (Mouse) Q9JKJ9
Entrez Gene ID: (Human) 51302, (Mouse) 56050
iron ion binding
steroid 7-alpha-hydroxylase activity
oxysterol 7-alpha-hydroxylase activity
heme binding
monooxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
24-hydroxycholesterol 7alpha-hydroxylase activity
metal ion binding
oxygenase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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