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Product Details
11771-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CYP4B1 Fusion Protein Ag2416 (211-512 aa encoded by BC017758)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SYYLAVSDL TLLMQQRLVS FQYHNDFIYW LTPHGRRFLR ACQVAHDHTD QVIRERKAAL QDEKVRKKIQ NRRHLDFLDI LLGARDEDDI KLSDADLRAE VDTFMFEGHD TTTSGISWFL YCMALYPEHQ HRCREEVREI LGDQDFFQWD DLGKMTYLTM CIKESFRLYP PVPQVYRQLS KPVTFVDGRS LPAGSLISMH IYALHRNSAV WPDPEVFDSL RFSTENASKR HPFAFMPFSA GPRNCIGQQF AMSEMKVVTA MCLLRFEFSL DPSRLPIKMP QLVLRSKNGF HLHLKPLGPG SGK (211-512 aa encoded by BC017758)
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CYPIVB1; Cytochrome P450 4B1; Cytochrome P450 isozyme 5; Cytochrome P450 L-2; cytochrome P450, family 4, subfamily B, polypeptide 1; cytochrome P450, subfamily 4B, polypeptide 1; cytochrome P450, subfamily IV B, polypeptide 1; cytochrome P450, subfamily IVB, polypeptide 1; Cytochrome P450-HP; microsomal monooxygenase; P450 L-2; P450-isozyme 5
Gene Aliases: Cyp4b-1; CYP4B1; CYPIVB1; P-450HP
UniProt ID: (Human) P13584, (Mouse) Q64462, (Rat) P15129
Entrez Gene ID: (Human) 1580, (Mouse) 13120, (Rat) 24307
iron ion binding
drug binding
toxic substance binding
fluorene oxygenase activity
oxygen binding
heme binding
aromatase activity
monooxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
metal ion binding
oxygenase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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