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Invitrogen
CaMKII beta/gamma Polyclonal Antibody
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FIGURE: 1 / 2
CaMKII beta/gamma Antibody (PA5-36195) in WB
Western blot analysis of CaMKII beta/gamma in Lane 1: U-87MG whole cell lysate (40 µg), Lane 2: PC3 whole cell lysate (40 µg), Lane 3: A549 whole cell lysate (40 µg), Lane 4: H9C2 whole cell lysate (40 µg), Lane 5: CT26 whole cell lysate (40 µg). Samples were incubated with CaMKII beta/gamma polyclonal antibody (Product # PA5-36195) at a dilution of 1:500.
Product Details
PA5-36195
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 601-652of human CaMKII beta
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 50-80 kDa.
Purity is >95% by SDS-PAGE.
Target Information
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be coexpressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: alternatively spliced; Ca++/calmodulin-dependent protein kinase II beta subunit; Ca2+/calmodulin-dependent protein kinase II; Calcium, calmodulin-dependent protein kinase; Calcium, calmodulin-dependent protein kinase II; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II gamma chain; Calcium/calmodulin-dependent protein kinase type II subunit beta; Calcium/calmodulin-dependent protein kinase type II subunit gamma; CaM kinase II beta subunit; CaM kinase II subunit beta; CaM kinase II subunit gamma; CaM-kinase II beta chain; caM-kinase II gamma chain; CaMK II; caMK-II subunit beta; caMK-II subunit gamma; proline rich calmodulin-dependent protein kinase; protein kinase homolog; unnamed protein product
Gene Aliases: CAM2; CAMK; CAMK-II; CAMK2; CAMK2B; Camk2d; CAMK2G; CAMKB; CAMKG; CaMKIIbeta; Ck2b; MRD54; MRD59
UniProt ID: (Human) Q13554, (Human) Q13555, (Rat) P08413, (Mouse) P28652, (Mouse) Q923T9, (Rat) P11730
Entrez Gene ID: (Human) 816, (Human) 818, (Rat) 24245, (Mouse) 12323, (Mouse) 12325, (Rat) 171140
nucleotide binding
actin binding
protein kinase activity
protein serine/threonine kinase activity
calmodulin-dependent protein kinase activity
protein binding
calmodulin binding
ATP binding
kinase activity
transferase activity
identical protein binding
protein homodimerization activity
protein serine kinase activity
calcium-dependent protein serine/threonine phosphatase activity
phospholipase binding
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
protein phosphorylation
signal transduction
nervous system development
positive regulation of neuron projection development
regulation of skeletal muscle adaptation
cell differentiation
protein autophosphorylation
regulation of neuronal synaptic plasticity
regulation of long-term neuronal synaptic plasticity
regulation of synapse structural plasticity
regulation of calcium ion transport
long-term synaptic potentiation
regulation of dendritic spine development
positive regulation of dendritic spine morphogenesis
positive regulation of synapse maturation
regulation of protein localization to plasma membrane
regulation of neuron migration
regulation of neuron projection development
insulin secretion
G1/S transition of mitotic cell cycle
inhibitory G-protein coupled receptor phosphorylation
calcium ion transport
peptidyl-serine phosphorylation
regulation of synaptic transmission, cholinergic
positive regulation of phospholipase A2 activity
response to cadmium ion
cell projection morphogenesis
neuromuscular process controlling balance
activation of meiosis involved in egg activation
positive regulation of apoptotic signaling pathway
phosphorylation
response to hypoxia
response to oxidative stress
multicellular organism development
protein oligomerization
regulation of relaxation of cardiac muscle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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