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Invitrogen
Calbindin Polyclonal Antibody
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FIGURE: 1 / 8
Calbindin Antibody (PA5-117824) in ICC/IF
Immunocytochemistry analysis of Calbindin in 293 cells. Samples were treated with 4% PFA, blocked with 10% serum, incubated with polyclonal antibody (Product # PA5-117824) with a dilution of 1:1,000 (4°C overnight), followed by Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (red).
Product Details
PA5-117824
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the N-terminus of the Human Calbindin
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calbindin; calbindin 1, (28kD); calbindin 1, 28kDa; calbindin 27; Calbindin D28; calbindin-D28k; D-28K; retrovirus-like H primer binding sequence protein; RTVL-H protein; unnamed protein product; Vitamin D-dependent calcium-binding protein, avian-type
Gene Aliases: CAB27; CALB; CALB1; D-28K
UniProt ID: (Human) P05937
Entrez Gene ID: (Human) 793
learning or memory
short-term memory
long-term memory
locomotory behavior
retina layer formation
response to auditory stimulus
metanephric part of ureteric bud development
regulation of synaptic plasticity
calcium ion homeostasis
retina development in camera-type eye
metanephric collecting duct development
metanephric distal convoluted tubule development
metanephric connecting tubule development
cochlea development
regulation of presynaptic cytosolic calcium ion concentration
regulation of postsynaptic cytosolic calcium ion concentration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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