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Exalpha
Calcium Channel (CACNA1B) Polyclonal Antibody
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Product Details
X1507P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from the rat alpha1B calcium channel conjugated to KLH
Conjugate
Form
Liquid
Concentration
0.5-2 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
0.08% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: Isoform Alpha-1b-1 and isoform Alpha-1b-2 are expressed in the central nervous system, but not in skeletal muscle or aorta.
Target Information
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BIII; Brain calcium channel III; calcium channel alpha12.2 subunit; calcium channel, L type, alpha-1 polypeptide; Calcium channel, L type, alpha-1 polypeptide isoform 5; calcium channel, voltage-dependent, L type, alpha 1B subunit; calcium channel, voltage-dependent, N type, alpha 1B subunit; Cav2.2 voltage-gated Ca2+ channel; Voltage-dependent N-type calcium channel subunit alpha-1B; voltage-gated calcium channel alpha subunit Cav2.2; Voltage-gated calcium channel subunit alpha Cav2.2
Gene Aliases: BIII; CACH5; CACNA1B; CACNL1A5; CACNN; Cav2.2; DYT23
UniProt ID: (Human) Q00975
Entrez Gene ID: (Human) 774
transport
chemical synaptic transmission
neurotransmitter secretion
locomotory behavior
regulation of heart contraction
regulation of blood pressure
regulation of ion transmembrane transport
response to pain
membrane depolarization
regulation of calcium ion transport
calcium ion transmembrane transport
membrane depolarization during action potential
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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