Search
Exalpha
Calcium Channel (CaV3.1) Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
X1510P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from the rat alpha1G calcium channel conjugated to KLH
Conjugate
Form
Liquid
Concentration
0.5-2 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
PBS
Contains
0.08% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: Rat brain lysate.
Target Information
Voltage-dependent Ca2+ channels mediate Ca2+ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca2+-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an alpha-1 subunit, an intracellular beta subunit, a disulfide linked alpha-2/delta subunit and a transmembrane gamma subunit. Ca2+ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca2+ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca2+ current types. T-type Ca2+ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Alpha1G-ae; Alpha1G-aef; Alpha1G-af; Alpha1G-bc; Alpha1G-bcd; Alpha1G-bce; Alpha1G-bcef; Alpha1G-be; CACNA1G-a; T-type; CACNA1G-b; T-type; calcium channel, voltage-dependent, T type, alpha 1G subunit; CaV T1; Cav3 1; cav3 1c; Cav3.1c; low voltage-activated T-type calcium channel alpha-1 subunit Cav3.1; low-voltage-activated calcium channel; MGC117234; NBR13; unnamed protein product; voltage-dependent calcium channel alpha 1G subunit; voltage-dependent T-type calcium channel alpha 1G subunit; Voltage-dependent T-type calcium channel subunit alpha-1G; voltage-gated calcium channel; Voltage-gated calcium channel subunit alpha Cav3.1
Gene Aliases: Ca(V)T.1; CACNA1G; Cav3.1; KIAA1123; NBR13; SCA42; SCA42ND
UniProt ID: (Human) O43497
Entrez Gene ID: (Human) 8913
ion channel activity
voltage-gated calcium channel activity
calcium channel activity
high voltage-gated calcium channel activity
low voltage-gated calcium channel activity
voltage-gated calcium channel activity involved in AV node cell action potential
voltage-gated calcium channel activity involved SA node cell action potential
scaffold protein binding
action potential
regulation of heart rate
sinoatrial node development
ion transport
calcium ion transport
chemical synaptic transmission
response to nickel cation
ion transmembrane transport
regulation of membrane potential
transmembrane transport
regulation of atrial cardiac muscle cell membrane depolarization
regulation of biological quality
calcium ion import
calcium ion transmembrane transport
cardiac muscle cell action potential involved in contraction
SA node cell action potential
AV node cell action potential
SA node cell to atrial cardiac muscle cell signalling
AV node cell to bundle of His cell signaling
membrane depolarization during AV node cell action potential
membrane depolarization during SA node cell action potential
regulation of heart rate by cardiac conduction
calcium ion import across plasma membrane
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support