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Invitrogen
Calcium Sensing Receptor Polyclonal Antibody
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FIGURE: 1 / 6
Calcium Sensing Receptor Antibody (PA5-33384) in IHC (P)
Immunohistochemistry analysis of Calcium Sensing Receptor in human Thyroid, Medullary Carcinoma. Samples were incubated with Calcium Sensing Receptor polyclonal antibody (Product # PA5-33384). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Product Details
PA5-33384
Product Specifications
Species Reactivity
Bat,
Bovine,
Dog,
Chicken,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Pig,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 17 amino acid peptide from N-terminal extracellular domain of human CASR.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G- protein that activates a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BoPCaR1; Ca sensing receptor; calcium receptor|CaR; calcium-sensing receptor; Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism); Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); CaR; CaSR; CaSR antibody; cation sensing receptor; Extracellular calcium-sensing receptor; G protein coupled receptor, family C, group 2, member A; G protein-coupled receptor, family C, group 2, member A; parathyroid Ca(2+)-sensing receptor 1; Parathyroid cell calcium-sensing receptor; Parathyroid cell calcium-sensing receptor 1; PCaR1
Gene Aliases: BoPCaR1; CAR; CASR; EIG8; FHH; FIH; GPRC2A; hCasR; HHC; HHC1; HYPOC1; NSHPT; PCAR1
UniProt ID: (Bovine) P35384, (Human) P41180, (Pig) O62714, (Rat) P48442, (Mouse) Q9QY96
G-protein coupled receptor activity
calcium ion binding
protein binding
amino acid binding
protein homodimerization activity
integrin binding
protein kinase binding
identical protein binding
ion channel binding
metal ion binding
magnesium ion binding
drug binding
polyamine binding
signal transducer activity
G-protein coupled receptor
ossification
detection of calcium ion
calcium ion transport
cellular calcium ion homeostasis
G-protein coupled receptor signaling pathway
JNK cascade
positive regulation of cell proliferation
positive regulation of gene expression
positive regulation of ATPase activity
vasodilation
calcium ion import
response to ischemia
signal transduction
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
chemosensory behavior
anatomical structure morphogenesis
response to metal ion
positive regulation of insulin secretion
bile acid secretion
cellular response to hepatocyte growth factor stimulus
positive regulation of vasoconstriction
branching morphogenesis of an epithelial tube
positive regulation of positive chemotaxis
response to calcium ion
regulation of calcium ion transport
fat pad development
positive regulation of ERK1 and ERK2 cascade
cellular response to vitamin D
cellular response to glucose stimulus
cellular response to low-density lipoprotein particle stimulus
cellular response to hypoxia
response to fibroblast growth factor
positive regulation of calcium ion import
regulation of presynaptic membrane potential
adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway
positive regulation of NLRP3 inflammasome complex assembly
cellular response to peptide
chloride transmembrane transport
apoptotic process
response to organic cyclic compound
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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