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|Tested species reactivity||Human, Mouse, Rabbit, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Purified rabbit skeletal muscle calreticulin.|
|Storage buffer||whole serum diluted in glycine buffered saline|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1/50-1/70|
|Western Blot (WB)||1/300-1/500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
Calreticulin is a 60kDa protein that has vital Ca2+ binding functions and is also involved in protein modification and folding within the endoplasmic reticulum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Defective transport of the obesity mutant PC1/3 N222D contributes to loss of function.
PA1-84481 was used in immunocytochemistry to study the cell biological mechinisms underlying the association with obesity of the PCSK1 pro-hormone convertase N222D mutation
|Prabhu Y,Blanco EH,Liu M,Peinado JR,Wheeler MC,Gekakis N,Arvan P,Lindberg I||Endocrinology (155:2391)||2014|
CABP3; CALBP; calcium-binding protein 3; calregulin; calreticulin; CRP55; endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; grp60; HACBP; Sicca syndrome antigen A (autoantigen Ro; calreticulin)
CALR; Calregulin; cC1qR; CRT; CRTC; HEL-S-99n; RO; SSA