Caspase-13 (also designated Evolutionarily related interleukin-1beta converting enzyme ; ERICE) involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. [subunit] Heterodimer of a small and a large subunit. The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8. Mainly expressed in peripheral blood lymphocytes, spleen and placenta. Belongs to peptidase family C14.
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Protein Aliases: apoptosis-related cysteine protease; CASP-13; CASP-4; caspase 4, apoptosis-related cysteine protease; Caspase-13; Caspase-13 subunit 1; Caspase-13 subunit 2; Caspase-4; Caspase-4 subunit 1; Caspase-4 subunit 2; ERICE; Evolutionary related interleukin-1-beta-converting enzyme
Gene Aliases: CASP13; CASP4
Entrez Gene ID: (Bovine) 338039