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Caspase-13 (also designated Evolutionarily related interleukin-1beta converting enzyme ; ERICE) involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. [subunit] Heterodimer of a small and a large subunit. The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8. Mainly expressed in peripheral blood lymphocytes, spleen and placenta. Belongs to peptidase family C14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apoptosis-related cysteine protease; CASP-13; CASP-4; caspase 4, apoptosis-related cysteine protease; Caspase-13; Caspase-13 subunit 1; Caspase-13 subunit 2; Caspase-4; Caspase-4 subunit 1; Caspase-4 subunit 2; ERICE; Evolutionary related interleukin-1-beta-converting enzyme
Gene Aliases: CASP13; CASP4
Entrez Gene ID: (Bovine) 338039
Molecular Function:
cysteine protease
enzyme modulator
hydrolase
protease
protease inhibitor
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