|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 58 of Human Caspase 2|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29156 targets Caspase 2 in WB applications and shows reactivity with Human samples.
The PA5-29156 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 58 of Human Caspase 2.
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CASP-2; caspase 2 apoptosis-related cysteine peptidase; Caspase-2; ICH1; NEDD-2; NEDD2; Neural precursor cell expressed developmentally down-regulated protein 2; PPP1R57; Protease ICH-1; protein phosphatase 1; protein phosphatase 1, regulatory subunit 57; regulatory subunit 57
Gene Aliases: CASP-2; CASP2; ICH1; NEDD-2; NEDD2; PPP1R57
UniProt ID: (Human) P42575
Entrez Gene ID: (Human) 835
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