Product References
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Translational stroke research
Lu D,Liu Y,Huang H,Hu M,Li T,Wang S,Shen S,Wu R,Cai W,Lu T,Lu Z
Fri Dec 01 00:00:00 UTC 2023
Ginsenoside Rh4 inhibits breast cancer growth through targeting histone deacetylase 2 to regulate immune microenvironment and apoptosis.
Bioorganic chemistry
Dong F,Qu L,Duan Z,He Y,Ma X,Fan D
Thu Jun 01 00:00:00 UTC 2023
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Molecular oncology
Luo G,Aldridge K,Chen T,Aslot V,Kim BG,Han EH,Singh N,Li S,Xiao TS,Sporn MB,Letterio JJ
Fri Dec 01 00:00:00 UTC 2023
Thymol Ameliorates Aspergillus fumigatus Keratitis by Downregulating the TLR4/ MyD88/ NF-kB/ IL-1β Signal Expression and Reducing Necroptosis and Pyroptosis.
Journal of microbiology and biotechnology
Wang L,Yan H,Chen X,Han L,Liu G,Yang H,Lu D,Liu W,Che C
Sat Jan 28 00:00:00 UTC 2023
The role of NADPH oxidase 1 in alcohol-induced oxidative stress injury of intestinal epithelial cells.
Cell biology and toxicology
Chen L,Chu H,Hu L,Li Z,Yang L,Hou X
Sun Oct 01 00:00:00 UTC 2023
Oridonin ameliorates caspase-9-mediated brain neuronal apoptosis in mouse with ischemic stroke by inhibiting RIPK3-mediated mitophagy.
Acta pharmacologica Sinica
Li L,Song JJ,Zhang MX,Zhang HW,Zhu HY,Guo W,Pan CL,Liu X,Xu L,Zhang ZY
Sat Apr 01 00:00:00 UTC 2023
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
European journal of medicinal chemistry
Lin H,Han H,Yang M,Wen Z,Chen Q,Ma Y,Wang X,Wang C,Yin T,Wang X,Lu G,Chen H,Qi J,Yang Y
Sun Mar 05 00:00:00 UTC 2023
UDP-glucuronate metabolism controls RIPK1-driven liver damage in nonalcoholic steatohepatitis.
Nature communications
Zhang T,Zhang N,Xing J,Zhang S,Chen Y,Xu D,Gu J
Thu May 11 00:00:00 UTC 2023
Danzhi Jiangtang capsule reduces renal injury in rats with diabetes induced by high fat diet and streptozotocin downregulating toll-like receptor 4-nuclear factor-κB pathway and apoptosis.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Jing X,Zheng BI,Sihai W,Guoming S,Zhaohui F
Sat Apr 01 00:00:00 UTC 2023
Necroptosis signaling and mitochondrial dysfunction cross-talking facilitate cell death mediated by chelerythrine in glioma.
Free radical biology & medicine
Wang P,Zheng SY,Jiang RL,Wu HD,Li YA,Lu JL,Xiong Y,Han B,Lin L
Thu Jun 01 00:00:00 UTC 2023
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Experimental biology and medicine (Maywood, N.J.)
Wang W,Gu Y,Ni H,Quan Q,Guo L
Thu Jun 01 00:00:00 UTC 2023
Ionizing Radiation Triggers the Antitumor Immunity by Inducing Gasdermin E-Mediated Pyroptosis in Tumor Cells.
International journal of radiation oncology, biology, physics
Cao W,Chen G,Wu L,Yu KN,Sun M,Yang M,Jiang Y,Jiang Y,Xu Y,Peng S,Han W
Wed Feb 01 00:00:00 UTC 2023
LACTB induces cancer cell death through the activation of the intrinsic caspase-independent pathway in breast cancer.
Apoptosis : an international journal on programmed cell death
Gonzalez-Morena JM,Escudeiro-Lopes S,Ferreira-Mendes JM,Jakoube P,Cutano V,Vinaixa-Forner J,Kralova Viziova P,Hartmanova A,Sedlacek R,Machado S,Malcekova B,Keckesova Z
Wed Feb 01 00:00:00 UTC 2023
A modified Fangji Huangqi decoction ameliorates pulmonary artery hypertension via phosphatidylinositide 3-kinases/protein kinase B-mediated regulation of proliferation and apoptosis of smooth muscle cells in vitro and in vivo.
Journal of ethnopharmacology
Xue Z,Zhou M,Liu Y,Qin H,Li Y,Zhu Y,Yang J
Thu Oct 05 00:00:00 UTC 2023
Sitravatinib as a potent FLT3 inhibitor can overcome gilteritinib resistance in acute myeloid leukemia.
Biomarker research
Zhang Y,Wang P,Wang Y,Shen Y
Tue Jan 24 00:00:00 UTC 2023
Hyperactivation of TRPV4 causes the hippocampal pyroptosis pathway and results in cognitive impairment in LPS-treated mice.
Behavioural brain research
Guo D,Xu Y,Wang Y,Zhong X,Liu Z,Li S,Xu X,Zhang J,Xiong T,Cao W,Liang J
Wed Feb 15 00:00:00 UTC 2023
A novel NEDD4L-TXNIP-CHOP axis in the pathogenesis of nonalcoholic steatohepatitis.
Theranostics
Guo Q,Xin M,Lu Q,Feng D,Yang V,Peng LF,Whelan KA,Hu W,Wu S,Yang X,Wang H,Rothberg BS,Gamero AM,Gerhard GS,Gao B,Yang L
Wed May 10 00:00:00 UTC 2023
Codelivery of TRAIL and Mitomycin C via Liposomes Shows Improved Antitumor Effect on TRAIL-Resistant Tumors.
Molecular pharmaceutics
Chang R,Fu R,Huang Y,Zhang J,Feng C,Wang R,Yan H,Li G,Chu X,Yuan F,Jia D,Li J
Mon Jun 05 00:00:00 UTC 2023
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
Journal of Cancer
Wang M,Zhang Y,Liu M,Jia Y,He J,Xu X,Shi H,Zhang Y,Zhang J,Liu Y
Sat Apr 15 00:00:00 UTC 2023
Combination with vorinostat enhances the antitumor activity of cisplatin in castration-resistant prostate cancer by inhibiting DNA damage repair pathway and detoxification of GSH.
The Prostate
Chang T,Lian Z,Ma S,Liang Z,Ma X,Wen X,Wang Y,Liu R
Sat Apr 01 00:00:00 UTC 2023
Abamectin causes toxicity to the carp respiratory system by triggering oxidative stress, inflammation, and apoptosis and inhibiting autophagy.
Environmental science and pollution research international
Feng H,Zhou P,Liu F,Zhang W,Yang H,Li X,Dong J
Sat Apr 01 00:00:00 UTC 2023
Sulforaphane Suppresses MCF-7 Breast Cancer Cells Growth via miR-19/PTEN Axis to Antagonize the Effect of Butyl Benzyl Phthalate.
Nutrition and cancer
Cao W,Lu X,Zhong C,Wu J
Mon Mar 20 00:00:00 UTC 2023
Macrophage lineage cells-derived migrasomes activate complement-dependent blood-brain barrier damage in cerebral amyloid angiopathy mouse model.
Nature communications
Hu M,Li T,Ma X,Liu S,Li C,Huang Z,Lin Y,Wu R,Wang S,Lu D,Lu T,Men X,Shen S,Huang H,Liu Y,Song K,Jian B,Jiang Y,Qiu W,Liu Q,Lu Z,Cai W
Tue Jul 04 00:00:00 UTC 2023
A role for fibroblast-derived SASP factors in the activation of pyroptotic cell death in mammary epithelial cells.
bioRxiv : the preprint server for biology
Hom LM,Sun S,Campbell J,Liu P,Culbert S,Murphy IM,Schafer ZT
Wed Feb 22 00:00:00 UTC 2023
Selenoprotein Gene mRNA Expression Evaluation During Renal Ischemia-Reperfusion Injury in Rats and Ebselen Intervention Effects.
Biological trace element research
Wu Y,Shi H,Xu Y,Wen R,Gong M,Hong G,Xu S
Sat Apr 01 00:00:00 UTC 2023
The Integrated Analysis of Transcriptomics and Metabolomics Unveils the Therapeutical Effect of Asiatic Acid on Alcoholic Hepatitis in Rats.
Inflammation
Chen S,Huang Y,Su H,Zhu W,Wei Y,Long Y,Shi Y,Wei J
Mon Aug 01 00:00:00 UTC 2022
Whole Genome Transcriptomic Analysis of Ovary Granulosa Cells Revealed an Anti-Apoptosis Regulatory Gene DLGAP5 in Polycystic Ovary Syndrome.
Frontiers in endocrinology
Deng Y,Li H,Song Y,Cen J,Zhang Y,Sui Y,Cui D,Li TC,Xu Y,Wang CC,Chung PWJ,Tang T
Tue Apr 05 00:00:00 UTC 2022
Inhibitory Effect of Lentivirus-Mediated Gag-Caspase-8 on the Growth of HER-2 Overexpressing Primary Human Breast Cancer Cells.
Cancer biotherapy & radiopharmaceuticals
Wang M,Li X,Xie W,Zhong L,Leng Y,Chen X,Yang M,Qi L,Zhang Z,Liu L,Tang D
Sat Oct 01 00:00:00 UTC 2022
Tilapia skin peptides, a by-product of fish processing, ameliorate DSS-induced colitis by regulating inflammation and inhibiting apoptosis.
Frontiers in nutrition
Gao J,Li L,Zhao D,Wang X,Xia Y,Li B,Liu C,Zuo X
Tue Oct 04 00:00:00 UTC 2022
Tilapia skin peptides, a by-product of fish processing, ameliorate DSS-induced colitis by regulating inflammation and inhibiting apoptosis.
Frontiers in nutrition
Gao J,Li L,Zhao D,Wang X,Xia Y,Li B,Liu C,Zuo X
Tue Oct 04 00:00:00 UTC 2022
Immunogenic cell death-related risk signature predicts prognosis and characterizes the tumour microenvironment in lower-grade glioma.
Frontiers in immunology
Cai J,Hu Y,Ye Z,Ye L,Gao L,Wang Y,Sun Q,Tong S,Yang J,Chen Q
Fri Nov 04 00:00:00 UTC 2022
Immunogenic cell death-related risk signature predicts prognosis and characterizes the tumour microenvironment in lower-grade glioma.
Frontiers in immunology
Cai J,Hu Y,Ye Z,Ye L,Gao L,Wang Y,Sun Q,Tong S,Yang J,Chen Q
Fri Nov 04 00:00:00 UTC 2022
Cyclic helix B peptide promotes random-pattern skin flap survival via TFE3-mediated enhancement of autophagy and reduction of ROS levels.
British journal of pharmacology
Lou J,Zhang H,Qi J,Xu Y,Wang X,Jiang J,Hu X,Ni L,Cai Y,Wang X,Gao W,Xiao J,Zhou K
Sat Jan 01 00:00:00 UTC 2022
Cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments.
In vitro cellular & developmental biology. Animal
Yang M,Feng J,Lan X,Tang Y,Zhang Y,Zhang H,Wang S
Tue Mar 01 00:00:00 UTC 2022
Expression levels of caspase-3 and gasdermin E and their involvement in the occurrence and prognosis of lung cancer.
Cancer reports (Hoboken, N.J.)
Huang YL,Zhang GH,Zhu Q,Wu X,Wu LG
Thu Sep 01 00:00:00 UTC 2022
Passive smoking induces rat testicular injury via the FAS/FASL pathway.
Drug and chemical toxicology
Yao Y,Zhang J,Tian P,Li L,Huang X,Nawutayi M,Huang Y,Zhang C
Sat Jan 01 00:00:00 UTC 2022
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Life sciences
Chen Q,Han H,Lin F,Yang L,Feng L,Lai X,Wen Z,Yang M,Wang C,Ma Y,Yin T,Lu G,Lin H,Qi J,Yang Y
Thu Dec 01 00:00:00 UTC 2022
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Pathology, research and practice
Li H,Liu J,Fan N,Wang H,Thomas AM,Yan Q,Li S,Qin H
Mon Aug 01 00:00:00 UTC 2022
New insights of necroptosis and immune infiltration in sepsis-induced myocardial dysfunction from bioinformatics analysis through RNA-seq in mice.
Frontiers in cellular and infection microbiology
Du Y,Zhong Y,Ding R,Wang X,Xia F,Zhang Q,Peng Q
Tue Jan 10 00:00:00 UTC 2023
Activation of CXCL13/CXCR5 axis aggravates experimental autoimmune cystitis and interstitial cystitis/bladder pain syndrome.
Biochemical pharmacology
Zhao J,Chen S,Yang C,Zhou M,Yang T,Sun B,Zhu J,Zhang H,Lu Q,Li L,Yang Z,Song B,Shen W,Yi S,Dai S
Wed Jun 01 00:00:00 UTC 2022
Fructose Induces Insulin Resistance of Gestational Diabetes Mellitus in Mice via the NLRP3 Inflammasome Pathway.
Frontiers in nutrition
Liu Y,Wei Y,Wu L,Lin X,Sun R,Chen H,Shen S,Deng G
Tue May 03 00:00:00 UTC 2022
PTX3 alleviates hard metal-induced acute lung injury through potentiating efferocytosis.
Ecotoxicology and environmental safety
Yan W,Ma D,Liu Y,Sun W,Cheng D,Li G,Zhou S,Wang Y,Wang H,Ni C
Sat Jan 15 00:00:00 UTC 2022
Intracranial delivery of synthetic mRNA to suppress glioblastoma.
Molecular therapy oncolytics
Peng H,Guo X,He J,Duan C,Yang M,Zhang X,Zhang L,Fu R,Wang B,Wang D,Chen H,Xie M,Feng P,Dai L,Tang X,Luo J
Thu Mar 17 00:00:00 UTC 2022
Involvement of caspase in patulin-induced hepatotoxicity in vitro and in vivo.
Toxicon : official journal of the International Society on Toxinology
Zhang B,Huang C,Lu Q,Liang H,Li J,Xu D
Sun Jan 30 00:00:00 UTC 2022
PCNP is a novel regulator of proliferation, migration, and invasion in human thyroid cancer.
International journal of biological sciences
Chen YG,Liu HX,Hong Y,Dong PZ,Liu SY,Gao YR,Lu D,Li T,Wang DY,Wu DD,Ji XY
Tue Jul 12 00:00:00 UTC 2022
SPTBN2 Promotes the Progression of Thyroid Cancer by Accelerating G1/S Transition and Inhibiting Apoptosis.
Disease markers
Zhou X,Lin L,Qi Y,Xu M,Xu Q,Wang Y,Qu J
Tue Aug 16 00:00:00 UTC 2022
JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE.
Brain research bulletin
Zhong X,Chen Z,Wang Y,Mao M,Deng Y,Shi M,Xu Y,Chen L,Cao W
Sat Oct 15 00:00:00 UTC 2022
Combined bulk RNA-seq and single-cell RNA-seq identifies a necroptosis-related prognostic signature associated with inhibitory immune microenvironment in glioma.
Frontiers in immunology
Wan S,Moure UAE,Liu R,Liu C,Wang K,Deng L,Liang P,Cui H
Tue Dec 06 00:00:00 UTC 2022
Combined bulk RNA-seq and single-cell RNA-seq identifies a necroptosis-related prognostic signature associated with inhibitory immune microenvironment in glioma.
Frontiers in immunology
Wan S,Moure UAE,Liu R,Liu C,Wang K,Deng L,Liang P,Cui H
Tue Dec 06 00:00:00 UTC 2022
Combined bulk RNA-seq and single-cell RNA-seq identifies a necroptosis-related prognostic signature associated with inhibitory immune microenvironment in glioma.
Frontiers in immunology
Wan S,Moure UAE,Liu R,Liu C,Wang K,Deng L,Liang P,Cui H
Tue Dec 06 00:00:00 UTC 2022
Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.
The Journal of biological chemistry
Zhou Y,Zheng R,Liu S,Disoma C,Du A,Li S,Chen Z,Dong Z,Zhang Y,Li S,Liu P,Razzaq A,Chen X,Liao Y,Tao S,Liu Y,Xu L,Zhang Q,Peng J,Deng X,Li S,Jiang T,Xia Z
Tue Feb 01 00:00:00 UTC 2022
Protective Effects of Vitamin C against Neomycin-Induced Apoptosis in HEI-OC1 Auditory Cell.
Neural plasticity
Gong L,Chen B,Chen J,Li Y
Tue May 24 00:00:00 UTC 2022
N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis.
Developmental cell
Du J,Sarkar R,Li Y,He L,Kang W,Liao W,Liu W,Nguyen T,Zhang L,Deng Z,Dougherty U,Kupfer SS,Chen M,Pekow J,Bissonnette M,He C,Li YC
Mon Aug 22 00:00:00 UTC 2022
Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A.
European journal of pharmacology
Huang Y,Chen S,Pang L,Feng Z,Su H,Zhu W,Wei J
Tue Feb 15 00:00:00 UTC 2022
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
International journal of biological sciences
Gou W,Luo N,Yu B,Wu H,Wu S,Tian C,Guo J,Ning H,Bi C,Wei H,Hou W,Li Y
Thu Apr 14 00:00:00 UTC 2022
Biotransformation of graphene oxide within lung fluids could intensify its synergistic biotoxicity effect with cadmium by inhibiting cellular efflux of cadmium.
Environmental pollution (Barking, Essex : 1987)
Zhu J,Liu L,Ma J,Fu Q,Zheng Z,Du E,Xu Y,Zhang Z
Mon Aug 01 00:00:00 UTC 2022
MiR-29a-3p Improves Acute Lung Injury by Reducing Alveolar Epithelial Cell PANoptosis.
Aging and disease
Cui Y,Wang X,Lin F,Li W,Zhao Y,Zhu F,Yang H,Rao M,Li Y,Liang H,Dai M,Liu B,Chen L,Han D,Lu R,Peng W,Zhang Y,Song C,Luo Y,Pan P
Wed Jun 01 00:00:00 UTC 2022
Antagonistic effects of selenium on lead-induced oxidative stress and apoptosis of Leydig cells in sheep.
Theriogenology
Shi L,Wang X,Duan Y,Li K,Ren Y
Wed Jun 01 00:00:00 UTC 2022
AMBRA1 promotes dsRNA- and virus-induced apoptosis through interacting with and stabilizing MAVS.
Journal of cell science
Lin Y,Huang C,Gao H,Li X,Lin Q,Zhou S,Huo Z,Huang Y,Liu C,Zhang P
Sat Jan 01 00:00:00 UTC 2022
Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage.
Cell death & disease
Lv Q,Han X,Ni J,Ma Q,Dai R,Liu J,Liu J,Zhai Y,Shen Q,Sun L,Liu H,Rao J,Xu H
Thu Oct 13 00:00:00 UTC 2022
FUNDC1 protects against doxorubicin-induced cardiomyocyte PANoptosis through stabilizing mtDNA via interaction with TUFM.
Cell death & disease
Bi Y,Xu H,Wang X,Zhu H,Ge J,Ren J,Zhang Y
Mon Dec 05 00:00:00 UTC 2022
Revealing the mechanism of Jiegeng decoction attenuates bleomycin-induced pulmonary fibrosis via PI3K/Akt signaling pathway based on lipidomics and transcriptomics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Xu Y,Wang X,Han D,Wang J,Luo Z,Jin T,Shi C,Zhou X,Lin L,Shan J
Wed Jul 20 00:00:00 UTC 2022
Caspase-8 is involved in pyroptosis, necroptosis and the maturation and release of IL-1β in Aspergillus fumigatus keratitis.
International immunopharmacology
Wang L,Yan H,Chen X,Lee J,Sun J,Liu G,Yang H,Lu D,Liu W,Che C
Thu Dec 01 00:00:00 UTC 2022
Caspase-8 is involved in pyroptosis, necroptosis and the maturation and release of IL-1β in Aspergillus fumigatus keratitis.
International immunopharmacology
Wang L,Yan H,Chen X,Lee J,Sun J,Liu G,Yang H,Lu D,Liu W,Che C
Thu Dec 01 00:00:00 UTC 2022
LncRNA HOTAIR promotes proliferation and suppresses apoptosis of mouse spermatogonium GC-1 cells by sponging miR-761 to modulate NANOS2 expression.
In vitro cellular & developmental biology. Animal
Kong X,Fei Q,Pan C,Jin J,Zheng J,Wu D,Li H,Huang X
Fri Apr 01 00:00:00 UTC 2022
RhFGF21 Protects Epidermal Cells against UVB-Induced Apoptosis through Activating AMPK-Mediated Autophagy.
International journal of molecular sciences
Zhao Y,Lin J,Li J,Bwalya C,Xu Y,Niu Y,Zhang Y,Wu J,Xu Y,Chen J,Ye S,Lin L
Tue Oct 18 00:00:00 UTC 2022
The Ameliorative Effect of JNK Inhibitor D-JNKI-1 on Neomycin-Induced Apoptosis in HEI-OC1 Cells.
Frontiers in molecular neuroscience
Zhao J,Liu H,Huang Z,Yang R,Gong L
Sat Apr 02 00:00:00 UTC 2022
Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms.
Nature communications
Grohmann C,Magtoto CM,Walker JR,Chua NK,Gabrielyan A,Hall M,Cobbold SA,Mieruszynski S,Brzozowski M,Simpson DS,Dong H,Dorizzi B,Jacobsen AV,Morrish E,Silke N,Murphy JM,Heath JK,Testa A,Maniaci C,Ciulli A,Lessene G,Silke J,Feltham R
Tue Apr 19 00:00:00 UTC 2022
Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis.
International journal of biological sciences
Dong L,Jiang H,Chen K,Xie J,An Q,Deng F,Sun Z,Liu Y,Zhou J,Zhang L,Lu X,Wang M,Chen Z,Zou X,Zuo D
Fri Apr 15 00:00:00 UTC 2022
Inhibition of STAT3Y705 phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells.
Cell death discovery
Guo H,Xiao Y,Yuan Z,Yang X,Chen J,Chen C,Wang M,Xie L,Chen Q,Tong Y,Zhang Q,Bai Y
Mon Mar 14 00:00:00 UTC 2022
Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.
Virulence
Jie W,Rui-Fen Z,Zhong-Xiang H,Yan W,Wei-Na L,Yong-Ping M,Jing S,Jing-Yi C,Wan-Hong L,Xiao-Hua H,Zhi L,Yan S
Thu Dec 01 00:00:00 UTC 2022
Site-Specific Integration of TRAIL in iPSC-Derived Mesenchymal Stem Cells for Targeted Cancer Therapy.
Stem cells translational medicine
Wang Z,Chen H,Wang P,Zhou M,Li G,Hu Z,Hu Q,Zhao J,Liu X,Wu L,Liang D
Thu Mar 31 00:00:00 UTC 2022
Nephrotoxicity evaluation of 3-monochloropropane-1,2-diol exposure in Sprague-Dawley rats using data-independent acquisition-based quantitative proteomics analysis.
Toxicology letters
Jin C,Min F,Zhong Y,Sun D,Luo R,Liu Q,Peng X
Tue Mar 01 00:00:00 UTC 2022
Tat-hspb1 Suppresses Clear Cell Renal Cell Carcinoma (ccRCC) Growth via Lysosomal Membrane Permeabilization.
Cancers
Zhang L,Jin GZ,Li D
Mon Nov 21 00:00:00 UTC 2022
Tat-hspb1 Suppresses Clear Cell Renal Cell Carcinoma (ccRCC) Growth via Lysosomal Membrane Permeabilization.
Cancers
Zhang L,Jin GZ,Li D
Mon Nov 21 00:00:00 UTC 2022
Hypoxia-preconditioned mesenchymal stem cells attenuate microglial pyroptosis after intracerebral hemorrhage.
Annals of translational medicine
Liu J,He J,Huang Y,Ge L,Xiao H,Zeng L,Jiang Z,Lu M,Hu Z
Wed Sep 01 00:00:00 UTC 2021
Traditional herbal formula Wu-Mei-Wan alleviates TNBS-induced colitis in mice by inhibiting necroptosis through increasing RIPK3 O-GlcNAcylation.
Chinese medicine
Wu F,Shao Q,Cheng Z,Xiong X,Fang K,Zhao Y,Dong R,Xu L,Lu F,Chen G
Mon Aug 16 00:00:00 UTC 2021
Paramylon from Euglena gracilis Prevents Lipopolysaccharide-Induced Acute Liver Injury.
Frontiers in immunology
Xie Y,Li J,Qin H,Wang Q,Chen Z,Liu C,Zheng L,Wang J
Thu Feb 24 00:00:00 UTC 2022
Oxidative stress-mediated apoptosis is involved in bisphenol S-induced reproductive toxicity in male C57BL/6 mice.
Journal of applied toxicology : JAT
Dai W,He QZ,Zhu BQ,Zeng HC
Mon Nov 01 00:00:00 UTC 2021
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
Food science & nutrition
Zhou S,Zhou Y,Yu J,Jiang L,Xiang Y,Wang J,Du Y,Cui X,Ge F
Thu Jul 01 00:00:00 UTC 2021
Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways.
Nutrition and cancer
Hu Z,Wang H,Fu Y,Ma K,Ma X,Wang J
Wed Sep 08 00:00:00 UTC 2021
VALD-3, a Schiff base ligand synthesized from o-vanillin derivatives, induces cell cycle arrest and apoptosis in breast cancer cells by inhibiting the Wnt/β-catenin pathway.
Scientific reports
Li H,Dang C,Tai X,Xue L,Meng Y,Ma S,Zhang J
Thu Jul 22 00:00:00 UTC 2021
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Clinical and experimental pharmacology & physiology
Lu C,Liu L,Chen S,Niu J,Li S,Xie W,Cheng X
Wed Dec 01 00:00:00 UTC 2021
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Clinical and experimental pharmacology & physiology
Lu C,Liu L,Chen S,Niu J,Li S,Xie W,Cheng X
Wed Dec 01 00:00:00 UTC 2021
Azathioprine pretreatment ameliorates myocardial ischaemia reperfusion injury in diabetic rats by reducing oxidative stress, apoptosis, and inflammation.
Clinical and experimental pharmacology & physiology
Lu C,Liu L,Chen S,Niu J,Li S,Xie W,Cheng X
Wed Dec 01 00:00:00 UTC 2021
MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL.
Communications biology
Nakabayashi O,Takahashi H,Moriwaki K,Komazawa-Sakon S,Ohtake F,Murai S,Tsuchiya Y,Koyahara Y,Saeki Y,Yoshida Y,Yamazaki S,Tokunaga F,Sawasaki T,Nakano H
Tue Jan 19 00:00:00 UTC 2021
Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.
Frontiers in cell and developmental biology
Cao W,Li Y,Sun H,Yang C,Zhu J,Xie C,Li X,Wu J,Geng S,Wang L,Sun L,Geng G,Han H,Zhong C
Fri Aug 06 00:00:00 UTC 2021
Gasdermin-E-mediated pyroptosis participates in the pathogenesis of Crohn's disease by promoting intestinal inflammation.
Cell reports
Tan G,Huang C,Chen J,Chen B,Zhi F
Tue Jun 15 00:00:00 UTC 2021
Curcuma oil ameliorates benign prostatic hyperplasia through suppression of the nuclear factor-kappa B signaling pathway in rats.
Journal of ethnopharmacology
Wang S,Li Y,Li W,Zhang K,Yuan Z,Cai Y,Xu K,Zhou J,Du Z
Thu Oct 28 00:00:00 UTC 2021
The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation.
Aging
Guo Y,Xiao Y,Guo H,Zhu H,Chen D,Wang J,Deng J,Lan J,Liu X,Zhang Q,Bai Y
Wed Jul 28 00:00:00 UTC 2021
Calcium alleviates fluoride-induced kidney damage via FAS/FASL, TNFR/TNF, DR5/TRAIL pathways in rats.
Ecotoxicology and environmental safety
Li H,Fan J,Zhao Y,Yang J,Xu H,Manthari RK,Cheng X,Wang J,Wang J
Wed Dec 15 00:00:00 UTC 2021
Lipidomic Alterations and PPARα Activation Induced by Resveratrol Lead to Reduction in Lesion Size in Endometriosis Models.
Oxidative medicine and cellular longevity
Chen Z,Wang C,Lin C,Zhang L,Zheng H,Zhou Y,Li X,Li C,Zhang X,Yang X,Guan M,Xi Y
Tue Feb 15 00:00:00 UTC 2022
Synergistic effects of AAGL and anti-PD-1 on hepatocellular carcinoma through lymphocyte recruitment to the liver.
Cancer biology & medicine
Ye X,Wang X,Yu W,Yang Q,Li Y,Jin Y,Su Y,Song J,Xu B,Sun H
Fri Mar 12 00:00:00 UTC 2021
TRAIL produced by SAM-1-activated CD4+ and CD8+ subgroup T cells induces apoptosis in human tumor cells through upregulation of death receptors.
Toxicology and applied pharmacology
Zhang G,Xu M,Zhang X,Ma L,Zhang H
Wed Sep 15 00:00:00 UTC 2021
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Evidence-based complementary and alternative medicine : eCAM
Liu K,Lv M,Ji X,Lou L,Nie B,Zhao J,Wu A,Zhao M
Sat Nov 13 00:00:00 UTC 2021
Anti-glioblastoma effects of nanomicelle-curcumin plus erlotinib.
Food & function
Bagherian A,Roudi B,Masoudian N,Mirzaei H
Mon Nov 01 00:00:00 UTC 2021
Infection of humanized mice with a novel phlebovirus presented pathogenic features of severe fever with thrombocytopenia syndrome.
PLoS pathogens
Xu S,Jiang N,Nawaz W,Liu B,Zhang F,Liu Y,Wu X,Wu Z
Sat May 01 00:00:00 UTC 2021
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Microorganisms
Yuan L,Chu B,Chen S,Li Y,Liu N,Zhu Y,Zhou D
Tue Nov 16 00:00:00 UTC 2021
Fisetin inhibits the proliferation, migration and invasion of pancreatic cancer by targeting PI3K/AKT/mTOR signaling.
Aging
Xiao Y,Liu Y,Gao Z,Li X,Weng M,Shi C,Wang C,Sun L
Thu Nov 25 00:00:00 UTC 2021
Selenite induced breast cancer MCF7 cells apoptosis through endoplasmic reticulum stress and oxidative stress pathway.
Chemico-biological interactions
Cao L,Zhang J,Du Y,Sun M,Xiang Y,Sheng Y,Ren X,Shao J
Mon Nov 01 00:00:00 UTC 2021
Expression and purification of a recombinant ELRL-MAP30 with dual-targeting anti-tumor bioactivity.
Protein expression and purification
Chen WW,Zhang HR,Huang ZG,Zhou ZY,Lou QW,Jiang XY,Zhu ZH
Wed Sep 01 00:00:00 UTC 2021
Construction of Smart Nanotheranostic Platform Bi-Ag@PVP: Multimodal CT/PA Imaging-Guided PDT/PTT for Cancer Therapy.
ACS omega
Zhou Z,Xie J,Ma S,Luo X,Liu J,Wang S,Chen Y,Yan J,Luo F
Tue Apr 27 00:00:00 UTC 2021
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
Bioorganic & medicinal chemistry
Qin J,Sun X,Ma Y,Cheng Y,Ma Q,Jing W,Qu S,Liu L
Fri Dec 31 00:00:00 UTC 2021
Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway.
Acta pharmacologica Sinica
Dong JY,Xia KJ,Liang W,Liu LL,Yang F,Fang XS,Xiong YJ,Wang L,Zhou ZJ,Li CY,Zhang WD,Wang JY,Chen DP
Wed Sep 01 00:00:00 UTC 2021
Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway.
Acta biochimica et biophysica Sinica
Pang B,Zhang J,Zhang X,Yuan J,Shi Y,Qiao L
Tue Mar 02 00:00:00 UTC 2021
sTNFRII-Fc modification protects human UC-MSCs against apoptosis/autophagy induced by TNF-α and enhances their efficacy in alleviating inflammatory arthritis.
Stem cell research & therapy
Zhao Y,Yang X,Li S,Zhang B,Li S,Wang X,Wang Y,Jia C,Chang Y,Wei W
Sat Oct 09 00:00:00 UTC 2021
Remarkable inhibition effects of afatinib alone or combining with paclitaxel in esophageal squamous cell carcinoma.
Journal of gastroenterology and hepatology
Yang LY,Cheng ZJ,Liu Z,Wang D,Zhang N,Fan ZL,Cai HQ,Zhang Y,Cai Y,Xu X,Wang JH,Du GH,Hao JJ,Wang MR
Wed Sep 01 00:00:00 UTC 2021
Lidocaine inhibits the metastatic potential of ovarian cancer by blocking NaV 1.5-mediated EMT and FAK/Paxillin signaling pathway.
Cancer medicine
Liu C,Yu M,Li Y,Wang H,Xu C,Zhang X,Li M,Guo H,Ma D,Guo X
Fri Jan 01 00:00:00 UTC 2021
Timolol induces necroptosis, apoptosis and senescence concentration-dependently in rabbit Limbal stem cells in vitro.
Life sciences
Jiang GJ,Li BB,Fan TJ
Thu Jul 15 00:00:00 UTC 2021
FNDC5/Irisin attenuates diabetic cardiomyopathy in a type 2 diabetes mouse model by activation of integrin αV/β5-AKT signaling and reduction of oxidative/nitrosative stress.
Journal of molecular and cellular cardiology
Lin C,Guo Y,Xia Y,Li C,Xu X,Qi T,Zhang F,Fan M,Hu G,Zhao H,Zhao H,Liu R,Gao E,Yan W,Tao L
Mon Nov 01 00:00:00 UTC 2021
Protective effect of Apelin/APJ system on lipopolysaccharide-related cardiac dysfunction.
General physiology and biophysics
Hu J,Huo S,Dou S,Jiang W,Li Y
Sat May 01 00:00:00 UTC 2021
Nfe2l1 deficiency mitigates streptozotocin-induced pancreatic β-cell destruction and development of diabetes in male mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Bao S,Zheng H,Chen C,Zhang Y,Bao L,Yang B,Hou Y,Chen Y,Zhang Q,Pi J,Fu J
Wed Dec 01 00:00:00 UTC 2021
HSPA13 facilitates NF-κB-mediated transcription and attenuates cell death responses in TNFα signaling.
Science advances
Gao C,Deng J,Zhang H,Li X,Gu S,Zheng M,Tang M,Zhu Y,Lin X,Jin J,Zhang L,Huang J,Zou J,Xia ZP,Xu PL,Shen L,Zhao B,Feng XH
Fri Oct 08 00:00:00 UTC 2021
Enterovirus 71 Induces INF2 Cleavage via Activated Caspase-2 in Infected RD Cells.
Frontiers in microbiology
Wang B,Zhang C,Yu C,Zhu Y,Tang Q,Huang H,Zhao Z
Sun May 30 00:00:00 UTC 2021
Adiponectin regulates osteocytic MLO-Y4 cell apoptosis in a high-glucose environment through the AMPK/FoxO3a signaling pathway.
Journal of cellular physiology
Zeng Y,Liang H,Guo Y,Feng Y,Yao Q
Fri Oct 01 00:00:00 UTC 2021
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Frontiers in pharmacology
Yang M,Li WY,Xie J,Wang ZL,Wen YL,Zhao CC,Tao L,Li LF,Tian Y,Sheng J
Sat May 08 00:00:00 UTC 2021
A new Mfn-2 related synthetic peptide promotes vascular smooth muscle cell apoptosis via regulating the mitochondrial apoptotic pathway by inhibiting Akt signaling.
Journal of translational medicine
Zhang X,Xu X,Lu L,Wan X,Qin Y,Ruan W,Lv C,He L,Guo X
Sun Sep 19 00:00:00 UTC 2021
Comparison of toxicity of Ti3 C2 and Nb2 C Mxene quantum dots (QDs) to human umbilical vein endothelial cells.
Journal of applied toxicology : JAT
Gu M,Dai Z,Yan X,Ma J,Niu Y,Lan W,Wang X,Xu Q
Sat May 01 00:00:00 UTC 2021
Fraxetin Inhibits the Proliferation and Metastasis of Glioma Cells by Inactivating JAK2/STAT3 Signaling.
Evidence-based complementary and alternative medicine : eCAM
Qu L,Lin P,Lin M,Ye S,Papa Akuetteh PD
Sat May 08 00:00:00 UTC 2021
SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States.
Cell reports
Wu K,Liu H,Wang Y,He J,Xu S,Chen Y,Kuang J,Liu J,Guo L,Li D,Shi R,Shen L,Wang Y,Zhang X,Wang J,Pei D,Chen J
Tue Jan 07 00:00:00 UTC 2020
Baohuoside-1 targeting mTOR inducing apoptsis to inhibit hepatocellular carcinoma proliferation, invasion and migration.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Guo Y,Zhu H,Weng M,Chen B,Wang C,Sun L
Sat Aug 01 00:00:00 UTC 2020
Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT).
PloS one
Nakano D,Kawaguchi T,Iwamoto H,Hayakawa M,Koga H,Torimura T
Thu Jul 23 00:00:00 UTC 2020
Baohuoside I via mTOR Apoptotic Signaling to Inhibit Glioma Cell Growth.
Cancer management and research
Guo Y,Wang C,Jiang M,Zhu H,Weng M,Sun L,Zhang Y
Mon Apr 18 00:00:00 UTC 2022
Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms.
Frontiers in pharmacology
Su W,Zhao J,Fan TJ
Mon Sep 28 00:00:00 UTC 2020
MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.
Chemico-biological interactions
Du J,Li J,Gao M,Guan Q,Liu T,Wu Y,Li Z,Zuo D,Zhang W,Wu Y
Mon May 25 00:00:00 UTC 2020
An integrated transcriptomics and network pharmacology approach to exploring the mechanism of adriamycin-induced kidney injury.
Chemico-biological interactions
He S,Li A,Zhang W,Zhang L,Liu Y,Li K,Qin X
Wed Jul 01 00:00:00 UTC 2020
miR-7112-3p targets PERK to regulate the endoplasmic reticulum stress pathway and apoptosis induced by photodynamic therapy in colorectal cancer CX-1 cells.
Photodiagnosis and photodynamic therapy
Kong F,Zou H,Liu X,He J,Zheng Y,Xiong L,Miao X
Sun Mar 01 00:00:00 UTC 2020
Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells.
Molecular medicine reports
Chi Z,Gao H,Liu H,Wu B,Zhang B,Gu M,Yang W
Sat Feb 01 00:00:00 UTC 2020
Palmatine induces G2/M phase arrest and mitochondrial-associated pathway apoptosis in colon cancer cells by targeting AURKA.
Biochemical pharmacology
Liu X,Zhang Y,Wu S,Xu M,Shen Y,Yu M,Fan J,Wei S,Xu C,Huang L,Zhao H,Li X,Ye X
Fri May 01 00:00:00 UTC 2020
Polymethoxyflavones from citrus inhibited gastric cancer cell proliferation through inducing apoptosis by upregulating RARβ, both in vitro and in vivo.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Wang Y,Chen Y,Zhang H,Chen J,Cao J,Chen Q,Li X,Sun C
Tue Dec 01 00:00:00 UTC 2020
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
Journal of Cancer
Yang B,Bai H,Sa Y,Zhu P,Liu P
Mon Sep 28 00:00:00 UTC 2020
Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis.
Cell proliferation
Peng F,Zhang N,Wang C,Wang X,Huang W,Peng C,He G,Han B
Wed Jan 01 00:00:00 UTC 2020
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice.
BioMed research international
Guo LP,Liu SX,Yang Q,Liu HY,Xu LL,Hao YH,Zhang XQ
Thu Jul 09 00:00:00 UTC 2020
Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo.
Chinese medicine
Lin HY,Han HW,Wang YS,He DL,Sun WX,Feng L,Wen ZL,Yang MK,Lu GH,Wang XM,Qi JL,Yang YH
Wed Apr 13 00:00:00 UTC 2022
Whole Transcriptome Analysis of Chicken Bursa Reveals Candidate Gene That Enhances the Host's Immune Response to Coccidiosis.
Frontiers in physiology
Guo L,Huang W,Tong F,Chen X,Cao S,Xu H,Luo W,Li Z,Nie Q
Tue Nov 17 00:00:00 UTC 2020
Low-dose naltrexone inhibits colorectal cancer progression and promotes apoptosis by increasing M1-type macrophages and activating the Bax/Bcl-2/caspase-3/PARP pathway.
International immunopharmacology
Ma M,Wang X,Liu N,Shan F,Feng Y
Mon Jun 01 00:00:00 UTC 2020
Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice.
Behavioural brain research
Liu Q,Guo X,Huang Z,He Q,Zhu D,Zhang S,Peng Z,Che Y,Feng X
Mon Apr 06 00:00:00 UTC 2020
Combination Therapy of Prostate Cancer by Oncolytic Adenovirus Harboring Interleukin 24 and Ionizing Radiation.
Frontiers in oncology
Mao LJ,Kan Y,Li BH,Ma S,Liu Y,Yang DL,Yang C
Mon Sep 28 00:00:00 UTC 2020
Combination Therapy of Prostate Cancer by Oncolytic Adenovirus Harboring Interleukin 24 and Ionizing Radiation.
Frontiers in oncology
Mao LJ,Kan Y,Li BH,Ma S,Liu Y,Yang DL,Yang C
Mon Sep 28 00:00:00 UTC 2020
PEGylated and Acylated Elabela Analogues Show Enhanced Receptor Binding, Prolonged Stability, and Remedy of Acute Kidney Injury.
Journal of medicinal chemistry
Wang C,Xiong M,Yang C,Yang D,Zheng J,Fan Y,Wang S,Gai Y,Lan X,Chen H,Zheng L,Huang K
Thu Dec 24 00:00:00 UTC 2020
Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress.
Pharmaceutical biology
Gou W,Luo N,Wei H,Wu H,Yu X,Duan Y,Bi C,Ning H,Hou W,Li Y
Tue Dec 01 00:00:00 UTC 2020
Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways.
Life sciences
Gao L,Qian B,Chen H,Wang A,Li Q,Li J,Tan P,Xia X,Du Y,Fu W
Fri May 15 00:00:00 UTC 2020
1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway.
Biochemical pharmacology
Zhou Y,Fu X,Guan Y,Gong M,He K,Huang B
Sat Feb 01 00:00:00 UTC 2020
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Ma Z,Yang J,Yang Y,Wang X,Chen G,Shi A,Lu Y,Jia S,Kang X,Lu L
Sun Mar 01 00:00:00 UTC 2020
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
Journal of cellular and molecular medicine
Dong P,Fu H,Chen L,Zhang S,Zhang X,Li H,Wu D,Ji X
Wed Jul 01 00:00:00 UTC 2020
Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Man S,Yang L,Xiang H,Lu G,Wang Y,Liu C,Gao W
Fri May 01 00:00:00 UTC 2020
Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells.
Toxicology in vitro : an international journal published in association with BIBRA
Yang T,Fan TJ,Xu B
Sat Aug 01 00:00:00 UTC 2020
Knockdown of fatty acid binding protein 4 exacerbates Bacillus Calmette-Guerin infection-induced RAW264.7 cell apoptosis via the endoplasmic reticulum stress pathway.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Yu J,Ma C,Xu Y,Han L,Wu X,Wang Y,Deng G
Sun Nov 01 00:00:00 UTC 2020
Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.
Innate immunity
Han L,Ma Q,Yu J,Gong Z,Ma C,Xu Y,Deng G,Wu X
Thu Oct 01 00:00:00 UTC 2020
Inhibition of Endoplasmic Reticulum Stress-Mediated Autophagy Enhances the Anticancer Effect of Iodine-125 Seed Radiation on Esophageal Squamous Cell Carcinoma.
Radiation research
Wang C,Li TK,Zeng CH,Yang J,Wang Y,Lu J,Zhu GY,Guo JH
Wed Sep 16 00:00:00 UTC 2020
Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo.
Life sciences
Liu J,Deng X,Sun X,Dong J,Huang J
Tue Sep 15 00:00:00 UTC 2020
Hypoxia-preconditioned olfactory mucosa mesenchymal stem cells abolish cerebral ischemia/reperfusion-induced pyroptosis and apoptotic death of microglial cells by activating HIF-1α.
Aging
Huang Y,Tan F,Zhuo Y,Liu J,He J,Duan D,Lu M,Hu Z
Sun Jun 07 00:00:00 UTC 2020
M10, a Myricetin-3-O-b-D-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in Mice.
Frontiers in pharmacology
Zhou XL,Yang J,Qu XJ,Meng J,Miao RR,Cui SX
Sun Apr 17 00:00:00 UTC 2022
Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis.
Redox biology
Wang N,Liu H,Liu G,Li M,He X,Yin C,Tu Q,Shen X,Bai W,Wang Q,Tao Y,Yin H
Fri May 01 00:00:00 UTC 2020
Inhibition of Specificity Protein 1 Is Involved in Phloretin-Induced Suppression of Prostate Cancer.
BioMed research international
Kang D,Zuo W,Wu Q,Zhu Q,Liu P
Thu Apr 29 00:00:00 UTC 2021
H3 Relaxin Alleviates Migration, Apoptosis and Pyroptosis Through P2X7R-Mediated Nucleotide Binding Oligomerization Domain-Like Receptor Protein 3 Inflammasome Activation in Retinopathy Induced by Hyperglycemia.
Frontiers in pharmacology
Yang K,Liu J,Zhang X,Ren Z,Gao L,Wang Y,Lin W,Ma X,Hao M,Kuang H
Tue Feb 16 00:00:00 UTC 2021
Active Peptide KF-8 from Rice Bran Attenuates Oxidative Stress in a Mouse Model of Aging Induced by d-Galactose.
Journal of agricultural and food chemistry
Wang Y,Cui X,Lin Q,Cai J,Tang L,Liang Y
Wed Nov 04 00:00:00 UTC 2020
Synergistic Utilization of Necrostatin-1 and Z-VAD-FMK Efficiently Promotes the Survival of Compression-Induced Nucleus Pulposus Cells via Alleviating Mitochondrial Dysfunction.
BioMed research international
Chen S,Tian Q,Shang C,Yang L,Wei N,Shang G,Ji Y,Kou H,Lu S,Liu H
Tue Jun 08 00:00:00 UTC 2021
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.
Molecular therapy : the journal of the American Society of Gene Therapy
Zhong B,Liu M,Bai C,Ruan Y,Wang Y,Qiu L,Hong Y,Wang X,Li L,Li B
Wed Apr 08 00:00:00 UTC 2020
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.
Molecular therapy : the journal of the American Society of Gene Therapy
Zhong B,Liu M,Bai C,Ruan Y,Wang Y,Qiu L,Hong Y,Wang X,Li L,Li B
Wed Apr 08 00:00:00 UTC 2020
ANP and BNP Exert Anti-Inflammatory Action via NPR-1/cGMP Axis by Interfering with Canonical, Non-Canonical, and Alternative Routes of Inflammasome Activation in Human THP1 Cells.
International journal of molecular sciences
Mezzasoma L,Talesa VN,Romani R,Bellezza I
Tue Dec 22 00:00:00 UTC 2020
A Novel Methoxybenzyl 5-Nitroacridone Derivative Effectively Triggers G1 Cell Cycle Arrest in Chronic Myelogenous Leukemia K562 Cells by Inhibiting CDK4/6-Mediated Phosphorylation of Rb.
International journal of molecular sciences
Zhang B,Zhang T,Zhang TY,Wang N,He S,Wu B,Jin HX
Sat Jul 18 00:00:00 UTC 2020
Tianma Gouteng Decoction Exerts Cardiovascular Protection by Upregulating OPG and TRAIL in Spontaneously Hypertensive Rats.
Evidence-based complementary and alternative medicine : eCAM
Deng LH,Li L,Zhai Y,Michael S,Yang CY,Guo R,Chen SF,Fan GW,Zhao YQ,Liu W
Tue Nov 03 00:00:00 UTC 2020
Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome.
Journal of cellular physiology
Li Y,Zheng Q,Sun D,Cui X,Chen S,Bulbul A,Liu S,Yan Q
Wed May 01 00:00:00 UTC 2019
Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome.
Journal of cellular physiology
Li Y,Zheng Q,Sun D,Cui X,Chen S,Bulbul A,Liu S,Yan Q
Wed May 01 00:00:00 UTC 2019
1,7-Bis(4-hydroxyphenyl)-1,4-heptadien-3-one induces lung cancer cell apoptosis via the PI3K/Akt and ERK1/2 pathways.
Journal of cellular physiology
Fan J,Wu M,Wang J,Ren D,Zhao J,Yang G
Wed May 01 00:00:00 UTC 2019
1,7-Bis(4-hydroxyphenyl)-1,4-heptadien-3-one induces lung cancer cell apoptosis via the PI3K/Akt and ERK1/2 pathways.
Journal of cellular physiology
Fan J,Wu M,Wang J,Ren D,Zhao J,Yang G
Wed May 01 00:00:00 UTC 2019
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
International immunopharmacology
He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B
Fri Mar 01 00:00:00 UTC 2019
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
International immunopharmacology
He Y,Xia Z,Yu D,Wang J,Jin L,Huang D,Ye X,Li X,Zhang B
Fri Mar 01 00:00:00 UTC 2019
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
International journal of food sciences and nutrition
Ge M,Zhang L,Cao L,Xie C,Li X,Li Y,Meng Y,Chen Y,Wang X,Chen J,Zhang Q,Shao J,Zhong C
Thu Aug 01 00:00:00 UTC 2019
Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.
International journal of food sciences and nutrition
Ge M,Zhang L,Cao L,Xie C,Li X,Li Y,Meng Y,Chen Y,Wang X,Chen J,Zhang Q,Shao J,Zhong C
Thu Aug 01 00:00:00 UTC 2019
Disruption of protein neddylation with MLN4924 attenuates paclitaxel-induced apoptosis and microtubule polymerization in ovarian cancer cells.
Biochemical and biophysical research communications
Hong X,Li S,Li W,Xie M,Wei Z,Guo H,Wei W,Zhang S
Tue Jan 15 00:00:00 UTC 2019
Disruption of protein neddylation with MLN4924 attenuates paclitaxel-induced apoptosis and microtubule polymerization in ovarian cancer cells.
Biochemical and biophysical research communications
Hong X,Li S,Li W,Xie M,Wei Z,Guo H,Wei W,Zhang S
Tue Jan 15 00:00:00 UTC 2019
Soluble CXCL16 promotes TNF-α-induced apoptosis in DLBCL via the AMAD10-NF-κB regulatory feedback loop.
Cell biology international
Yang H,Qiu B,Chen S,Xun Y,Pan Y,Chen M,Li WX,Liao W,El-Ashram S,Yang A,Liu F
Thu Aug 01 00:00:00 UTC 2019
Mechanisms of IFNalpha-1a-Induced Apoptosis in a Laryngeal Cancer Cell Line.
Medical science monitor : international medical journal of experimental and clinical research
Xin XL,Zhang R,Yuan XM,Liu L
Sun Sep 22 00:00:00 UTC 2019
Silencing of lncRNA HOXA11-AS inhibits cell migration, invasion, proliferation, and promotes apoptosis in human glioma cells via upregulating microRNA-125a: in vitro and in vivo studies.
American journal of translational research
Jiang J,Wang X,Gao G,Liu X,Chang H,Xiong R,Lu J,Sun Z
Thu Oct 01 00:00:00 UTC 2020
Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo.
Journal of biomedical nanotechnology
Zhang D,Zhang J,Zeng J,Li Z,Zuo H,Huang C,Zhao X
Fri Feb 01 00:00:00 UTC 2019
Moderate activation of Wnt/β-catenin signaling promotes the survival of rat nucleus pulposus cells via regulating apoptosis, autophagy, and senescence.
Journal of cellular biochemistry
Li Z,Chen S,Chen S,Huang D,Ma K,Shao Z
Thu Aug 01 00:00:00 UTC 2019
Peptide V3 Inhibits the Growth of Human Hepatocellular Carcinoma by Inhibiting the Ras/Raf/MEK/ERK Signaling Pathway.
Journal of Cancer
Wu D,Li M,Gao Y,Tian W,Li J,Zhang Q,Liu Z,Zheng M,Wang H,Wang J,Teng T,Zhang L,Ji X,Xie Z,Ji A,Li Y
Tue Sep 29 00:00:00 UTC 2020
Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure.
Clinical epigenetics
Huang Y,Ren A,Wang L,Jin L,Lin S,Li Z,McDonald JA
Tue May 07 00:00:00 UTC 2019
Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.
Phytotherapy research : PTR
Zhang Q,Cao WS,Wang XQ,Zhang M,Lu XM,Chen JQ,Chen Y,Ge MM,Zhong CY,Han HY
Tue Oct 01 00:00:00 UTC 2019
Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis.
Scientific reports
Li Z,Yu Y,Wang M,Xu H,Han B,Jiang P,Ma H,Li Y,Tian C,Zhou D,Li X,Ye X
Wed Jan 16 00:00:00 UTC 2019
Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis.
Scientific reports
Li Z,Yu Y,Wang M,Xu H,Han B,Jiang P,Ma H,Li Y,Tian C,Zhou D,Li X,Ye X
Wed Jan 16 00:00:00 UTC 2019
Long noncoding RNA UBE2R2-AS1 promotes glioma cell apoptosis via targeting the miR-877-3p/TLR4 axis.
OncoTargets and therapy
Xu W,Hu GQ,Da Costa C,Tang JH,Li QR,Du L,Pan YW,Lv SQ
Thu Oct 01 00:00:00 UTC 2020
PFKFB3 promotes endotoxemia-induced myocardial dysfunction through inflammatory signaling and apoptotic induction.
Toxicology and applied pharmacology
Tian W,Guo HS,Li CY,Cao W,Wang XY,Mo D,Hao XW,Feng YD,Sun Y,Lei F,Zhang HN,Zhao MG,Li XQ
Mon Apr 01 00:00:00 UTC 2019
Viral Nonstructural Protein 1 Induces Mitochondrion-Mediated Apoptosis in Mink Enteritis Virus Infection.
Journal of virology
Lin P,Cheng Y,Song S,Qiu J,Yi L,Cao Z,Li J,Cheng S,Wang J
Fri Nov 15 00:00:00 UTC 2019
Cloning of a new testis-enriched gene C4orf22 and its role in cell cycle and apoptosis in mouse spermatogenic cells.
Molecular biology reports
Li H,Dai Y,Luo Z,Nie D
Mon Apr 01 00:00:00 UTC 2019
Loss of periodontal ligament fibroblasts by RIPK3-MLKL-mediated necroptosis in the progress of chronic periodontitis.
Scientific reports
Shi J,Li J,Su W,Zhao S,Li H,Lei L
Wed Feb 27 00:00:00 UTC 2019
Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1β During Mycobacterium bovis Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation.
Frontiers in immunology
Liao Y,Hussain T,Liu C,Cui Y,Wang J,Yao J,Chen H,Song Y,Sabir N,Hussain M,Zhao D,Zhou X
Tue Jul 21 00:00:00 UTC 2020
Multi-Walled Carbon Nanotubes (MWCNTs) Activate Apoptotic Pathway Through ER Stress: Does Surface Chemistry Matter?
International journal of nanomedicine
Sun Y,Gong J,Cao Y
Thu Feb 20 00:00:00 UTC 2020
Induction of Inflammatory Macrophages in the Gut and Extra-Gut Tissues by Colitis-Mediated Escherichia coli.
iScience
Qi H,Gao Y,Li Y,Wei J,Su X,Zhang C,Liu Y,Zhu H,Sui L,Xiong Y,Yang X,Xu Y,Zhang Y,Yang R
Fri Nov 22 00:00:00 UTC 2019
EPO regulates neuroprotective Transmembrane BAX Inhibitor-1 Motif-containing (TMBIM) family members GRINA and FAIM2 after cerebral ischemia-reperfusion injury.
Experimental neurology
Habib P,Stamm AS,Zeyen T,Noristani R,Slowik A,Beyer C,Wilhelm T,Huber M,Komnig D,Schulz JB,Reich A
Tue Oct 01 00:00:00 UTC 2019
Arsenic-induced cardiotoxicity correlates with mitochondrial damage and trace elements imbalance in broiler chickens.
Poultry science
Li S,Zhao H,Wang Y,Shao Y,Liu J,Xing M
Fri Feb 01 00:00:00 UTC 2019
Arsenic-induced cardiotoxicity correlates with mitochondrial damage and trace elements imbalance in broiler chickens.
Poultry science
Li S,Zhao H,Wang Y,Shao Y,Liu J,Xing M
Fri Feb 01 00:00:00 UTC 2019
PPAR δ inhibition protects against palmitic acid-LPS induced lipidosis and injury in cultured hepatocyte L02 cell.
International journal of medical sciences
Li Y,Wang C,Lu J,Huang K,Han Y,Chen J,Yang Y,Liu B
Thu Apr 30 00:00:00 UTC 2020
p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer.
Journal of cellular and molecular medicine
Yan XY,Zhong XR,Yu SH,Zhang LC,Liu YN,Zhang Y,Sun LK,Su J
Sat Jun 01 00:00:00 UTC 2019
p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer.
Journal of cellular and molecular medicine
Yan XY,Zhong XR,Yu SH,Zhang LC,Liu YN,Zhang Y,Sun LK,Su J
Sat Jun 01 00:00:00 UTC 2019
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Cancer letters
Wang J,Tian L,Khan MN,Zhang L,Chen Q,Zhao Y,Yan Q,Fu L,Liu J
Wed Feb 28 00:00:00 UTC 2018
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Cancer letters
Wang J,Tian L,Khan MN,Zhang L,Chen Q,Zhao Y,Yan Q,Fu L,Liu J
Wed Feb 28 00:00:00 UTC 2018
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Life sciences
Xiao Y,Tian C,Huang T,Han B,Wang M,Ma H,Li Z,Ye X,Li X
Mon Jan 01 00:00:00 UTC 2018
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Life sciences
Xiao Y,Tian C,Huang T,Han B,Wang M,Ma H,Li Z,Ye X,Li X
Mon Jan 01 00:00:00 UTC 2018
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Life sciences
Xiao Y,Tian C,Huang T,Han B,Wang M,Ma H,Li Z,Ye X,Li X
Mon Jan 01 00:00:00 UTC 2018
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Life sciences
Xiao Y,Tian C,Huang T,Han B,Wang M,Ma H,Li Z,Ye X,Li X
Mon Jan 01 00:00:00 UTC 2018
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Phytotherapy research : PTR
Chen Y,Li Y,Wang XQ,Meng Y,Zhang Q,Zhu JY,Chen JQ,Cao WS,Wang XQ,Xie CF,Li XT,Geng SS,Wu JS,Zhong CY,Han HY
Sat Dec 01 00:00:00 UTC 2018
Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway.
Phytotherapy research : PTR
Chen Y,Li Y,Wang XQ,Meng Y,Zhang Q,Zhu JY,Chen JQ,Cao WS,Wang XQ,Xie CF,Li XT,Geng SS,Wu JS,Zhong CY,Han HY
Sat Dec 01 00:00:00 UTC 2018
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Food & function
Liu Y,Fan D
Wed Nov 14 00:00:00 UTC 2018
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Food & function
Liu Y,Fan D
Wed Nov 14 00:00:00 UTC 2018
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Food & function
Liu Y,Fan D
Wed Nov 14 00:00:00 UTC 2018
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Food & function
Liu Y,Fan D
Wed Nov 14 00:00:00 UTC 2018
Neferine, a Bisbenzylisoquinoline Alkaloid, Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis.
The American journal of Chinese medicine
Wu X,Guo Y,Min X,Pei L,Chen X
Tue Dec 18 00:00:00 UTC 2018
Neferine, a Bisbenzylisoquinoline Alkaloid, Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis.
The American journal of Chinese medicine
Wu X,Guo Y,Min X,Pei L,Chen X
Tue Dec 18 00:00:00 UTC 2018
Discovery and Characterization of 4-Hydroxy-2-pyridone Derivative Sambutoxin as a Potent and Promising Anticancer Drug Candidate: Activity and Molecular Mechanism.
Molecular pharmaceutics
Li LN,Wang L,Cheng YN,Cao ZQ,Zhang XK,Guo XL
Mon Nov 05 00:00:00 UTC 2018
Discovery and Characterization of 4-Hydroxy-2-pyridone Derivative Sambutoxin as a Potent and Promising Anticancer Drug Candidate: Activity and Molecular Mechanism.
Molecular pharmaceutics
Li LN,Wang L,Cheng YN,Cao ZQ,Zhang XK,Guo XL
Mon Nov 05 00:00:00 UTC 2018
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
Journal of cellular and molecular medicine
Wu J,Xing C,Zhang L,Mao H,Chen X,Liang M,Wang F,Ren H,Cui H,Jiang A,Wang Z,Zou M,Ji Y
Thu Feb 01 00:00:00 UTC 2018
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
Journal of cellular and molecular medicine
Wu J,Xing C,Zhang L,Mao H,Chen X,Liang M,Wang F,Ren H,Cui H,Jiang A,Wang Z,Zou M,Ji Y
Thu Feb 01 00:00:00 UTC 2018
Alterations of antioxidant indexes and inflammatory cytokine expression aggravated hepatocellular apoptosis through mitochondrial and death receptor-dependent pathways in Gallus gallus exposed to arsenic and copper.
Environmental science and pollution research international
Liu J,Zhao H,Wang Y,Shao Y,Li J,Xing M
Fri Jun 01 00:00:00 UTC 2018
Alterations of antioxidant indexes and inflammatory cytokine expression aggravated hepatocellular apoptosis through mitochondrial and death receptor-dependent pathways in Gallus gallus exposed to arsenic and copper.
Environmental science and pollution research international
Liu J,Zhao H,Wang Y,Shao Y,Li J,Xing M
Fri Jun 01 00:00:00 UTC 2018
MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway.
Cancer biology & therapy
Yin S,Du W,Wang F,Han B,Cui Y,Yang D,Chen H,Liu D,Liu X,Zhai X,Jiang C
Tue Apr 03 00:00:00 UTC 2018
MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway.
Cancer biology & therapy
Yin S,Du W,Wang F,Han B,Cui Y,Yang D,Chen H,Liu D,Liu X,Zhai X,Jiang C
Tue Apr 03 00:00:00 UTC 2018
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Journal of cellular biochemistry
Li X,Meng Y,Xie C,Zhu J,Wang X,Li Y,Geng S,Wu J,Zhong C,Li M
Tue May 01 00:00:00 UTC 2018
Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway.
Journal of cellular biochemistry
Li X,Meng Y,Xie C,Zhu J,Wang X,Li Y,Geng S,Wu J,Zhong C,Li M
Tue May 01 00:00:00 UTC 2018
Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice.
Toxicology and applied pharmacology
Guo Y,Wu X,Wu Q,Lu Y,Shi J,Chen X
Sun Apr 01 00:00:00 UTC 2018
Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice.
Toxicology and applied pharmacology
Guo Y,Wu X,Wu Q,Lu Y,Shi J,Chen X
Sun Apr 01 00:00:00 UTC 2018
Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis.
Clinical implant dentistry and related research
Che C,Liu J,Yang J,Ma L,Bai N,Zhang Q
Fri Jun 01 00:00:00 UTC 2018
Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis.
Clinical implant dentistry and related research
Che C,Liu J,Yang J,Ma L,Bai N,Zhang Q
Fri Jun 01 00:00:00 UTC 2018
Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of Pancreatic Cancer BxPC-3 Cell Line via a RhoGDI2/Rac1/NF-κB Signaling Pathway.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Zhang M,Ding G,Zhou L,Shen T,Xu X,Zhao T,Jia S,Cao L
Sat Sep 01 00:00:00 UTC 2018
Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of Pancreatic Cancer BxPC-3 Cell Line via a RhoGDI2/Rac1/NF-κB Signaling Pathway.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Zhang M,Ding G,Zhou L,Shen T,Xu X,Zhao T,Jia S,Cao L
Sat Sep 01 00:00:00 UTC 2018
Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis.
Cornea
Zhao W,Che C,Liu K,Zhang J,Jiang N,Yuan K,Zhao G
Sat Dec 01 00:00:00 UTC 2018
Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis.
Cornea
Zhao W,Che C,Liu K,Zhang J,Jiang N,Yuan K,Zhao G
Sat Dec 01 00:00:00 UTC 2018
β-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors.
International journal of oncology
You C,Zhang S,Sun Y,Zhang S,Tang G,Tang F,Liu X,Xiao Y,Zhang J,Gong Y,Xie C
Thu Nov 01 00:00:00 UTC 2018
PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways.
BMC cancer
Wu DD,Gao YR,Li T,Wang DY,Lu D,Liu SY,Hong Y,Ning HB,Liu JP,Shang J,Shi JF,Wei JS,Ji XY
Wed May 02 00:00:00 UTC 2018
PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways.
BMC cancer
Wu DD,Gao YR,Li T,Wang DY,Lu D,Liu SY,Hong Y,Ning HB,Liu JP,Shang J,Shi JF,Wei JS,Ji XY
Wed May 02 00:00:00 UTC 2018
MicroRNA-93 mediates cabergoline-resistance by targeting ATG7 in prolactinoma.
The Journal of endocrinology
Wu Z,Cai L,Lu J,Wang C,Guan J,Chen X,Wu J,Zheng W,Wu Z,Li Q,Su Z
Sat Sep 01 00:00:00 UTC 2018
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Frontiers in pharmacology
Mao J,Yi M,Wang R,Huang Y,Chen M
Sat Apr 09 00:00:00 UTC 2022
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Frontiers in pharmacology
Mao J,Yi M,Wang R,Huang Y,Chen M
Sat Apr 09 00:00:00 UTC 2022
Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zheng Q,Zhou F,Cui X,Liu M,Li Y,Liu S,Tan J,Yan Q
Fri Aug 17 00:00:00 UTC 2018
Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zheng Q,Zhou F,Cui X,Liu M,Li Y,Liu S,Tan J,Yan Q
Fri Aug 17 00:00:00 UTC 2018
Polybrominated Diphenyl Ethers Quinone Induced Parthanatos-like Cell Death through a Reactive Oxygen Species-Associated Poly(ADP-ribose) Polymerase 1 Signaling.
Chemical research in toxicology
Dong W,Yang B,Wang Y,Yuan J,Fan Y,Song E,Song Y
Mon Nov 19 00:00:00 UTC 2018
Role of Daucosterol Linoleate on Breast Cancer: Studies on Apoptosis and Metastasis.
Journal of agricultural and food chemistry
Han B,Jiang P,Liu W,Xu H,Li Y,Li Z,Ma H,Yu Y,Li X,Ye X
Wed Jun 20 00:00:00 UTC 2018
A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination.
The EMBO journal
Wang X,Cao W,Zhang J,Yan M,Xu Q,Wu X,Wan L,Zhang Z,Zhang C,Qin X,Xiao M,Ye D,Liu Y,Han Z,Wang S,Mao L,Wei W,Chen W
Tue May 02 00:00:00 UTC 2017
A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination.
The EMBO journal
Wang X,Cao W,Zhang J,Yan M,Xu Q,Wu X,Wan L,Zhang Z,Zhang C,Qin X,Xiao M,Ye D,Liu Y,Han Z,Wang S,Mao L,Wei W,Chen W
Tue May 02 00:00:00 UTC 2017
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Chemosphere
Li S,Zhao H,Wang Y,Shao Y,Li J,Liu J,Xing M
Fri Dec 01 00:00:00 UTC 2017
The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart.
Chemosphere
Li S,Zhao H,Wang Y,Shao Y,Li J,Liu J,Xing M
Fri Dec 01 00:00:00 UTC 2017
The Circadian Gene Clock Regulates Bone Formation Via PDIA3.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Yuan G,Hua B,Yang Y,Xu L,Cai T,Sun N,Yan Z,Lu C,Qian R
Sat Apr 01 00:00:00 UTC 2017
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Phytotherapy research : PTR
Zhu JY,Yang X,Chen Y,Jiang Y,Wang SJ,Li Y,Wang XQ,Meng Y,Zhu MM,Ma X,Huang C,Wu R,Xie CF,Li XT,Geng SS,Wu JS,Zhong CY,Han HY
Sat Apr 01 00:00:00 UTC 2017
Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways.
Phytotherapy research : PTR
Zhu JY,Yang X,Chen Y,Jiang Y,Wang SJ,Li Y,Wang XQ,Meng Y,Zhu MM,Ma X,Huang C,Wu R,Xie CF,Li XT,Geng SS,Wu JS,Zhong CY,Han HY
Sat Apr 01 00:00:00 UTC 2017
A novel regulatory network among LncRpa, CircRar1, MiR-671 and apoptotic genes promotes lead-induced neuronal cell apoptosis.
Archives of toxicology
Nan A,Chen L,Zhang N,Liu Z,Yang T,Wang Z,Yang C,Jiang Y
Sat Apr 01 00:00:00 UTC 2017
A novel regulatory network among LncRpa, CircRar1, MiR-671 and apoptotic genes promotes lead-induced neuronal cell apoptosis.
Archives of toxicology
Nan A,Chen L,Zhang N,Liu Z,Yang T,Wang Z,Yang C,Jiang Y
Sat Apr 01 00:00:00 UTC 2017
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
The Journal of nutritional biochemistry
Zhu J,Wang S,Chen Y,Li X,Jiang Y,Yang X,Li Y,Wang X,Meng Y,Zhu M,Ma X,Huang C,Wu R,Xie C,Geng S,Wu J,Zhong C,Han H
Thu Jun 01 00:00:00 UTC 2017
miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells.
The Journal of nutritional biochemistry
Zhu J,Wang S,Chen Y,Li X,Jiang Y,Yang X,Li Y,Wang X,Meng Y,Zhu M,Ma X,Huang C,Wu R,Xie C,Geng S,Wu J,Zhong C,Han H
Thu Jun 01 00:00:00 UTC 2017
Dectin-1 is essential for IL-1β production through JNK activation and apoptosis in Aspergillus fumigatus keratitis.
International immunopharmacology
Yuan K,Zhao G,Che C,Li C,Lin J,Zhu G,He K
Wed Nov 01 00:00:00 UTC 2017
Dectin-1 is essential for IL-1β production through JNK activation and apoptosis in Aspergillus fumigatus keratitis.
International immunopharmacology
Yuan K,Zhao G,Che C,Li C,Lin J,Zhu G,He K
Wed Nov 01 00:00:00 UTC 2017
Relaxin attenuates aristolochic acid induced human tubular epithelial cell apoptosis in vitro by activation of the PI3K/Akt signaling pathway.
Apoptosis : an international journal on programmed cell death
Xie XC,Zhao N,Xu QH,Yang X,Xia WK,Chen Q,Wang M,Fei X
Thu Jun 01 00:00:00 UTC 2017
Relaxin attenuates aristolochic acid induced human tubular epithelial cell apoptosis in vitro by activation of the PI3K/Akt signaling pathway.
Apoptosis : an international journal on programmed cell death
Xie XC,Zhao N,Xu QH,Yang X,Xia WK,Chen Q,Wang M,Fei X
Thu Jun 01 00:00:00 UTC 2017
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
International journal of molecular medicine
Wang H,Xu YS,Wang ML,Cheng C,Bian R,Yuan H,Wang Y,Guo T,Zhu LL,Zhou H
Sat Apr 01 00:00:00 UTC 2017
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
International journal of molecular medicine
Wang H,Xu YS,Wang ML,Cheng C,Bian R,Yuan H,Wang Y,Guo T,Zhu LL,Zhou H
Sat Apr 01 00:00:00 UTC 2017
12-Chloracetyl-PPD, a novel dammarane derivative, shows anti-cancer activity via delay the progression of cell cycle G2/M phase and reactive oxygen species-mediate cell apoptosis.
European journal of pharmacology
Wang X,Sun YY,Zhao C,Qu FZ,Zhao YQ
Sun Mar 05 00:00:00 UTC 2017
12-Chloracetyl-PPD, a novel dammarane derivative, shows anti-cancer activity via delay the progression of cell cycle G2/M phase and reactive oxygen species-mediate cell apoptosis.
European journal of pharmacology
Wang X,Sun YY,Zhao C,Qu FZ,Zhao YQ
Sun Mar 05 00:00:00 UTC 2017
Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Tang Q,Ji F,Wang J,Guo L,Li Y,Bao Y
Wed Nov 15 00:00:00 UTC 2017
Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Tang Q,Ji F,Wang J,Guo L,Li Y,Bao Y
Wed Nov 15 00:00:00 UTC 2017
Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.
Journal of Cancer
Mehmood T,Maryam A,Tian X,Khan M,Ma T
Wed Mar 30 00:00:00 UTC 2022
Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.
Journal of Cancer
Mehmood T,Maryam A,Tian X,Khan M,Ma T
Wed Mar 30 00:00:00 UTC 2022
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Biochemical and biophysical research communications
Zhu J,Jiang Y,Yang X,Wang S,Xie C,Li X,Li Y,Chen Y,Wang X,Meng Y,Zhu M,Wu R,Huang C,Ma X,Geng S,Wu J,Zhong C
Sun Jan 01 00:00:00 UTC 2017
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells.
Biochemical and biophysical research communications
Zhu J,Jiang Y,Yang X,Wang S,Xie C,Li X,Li Y,Chen Y,Wang X,Meng Y,Zhu M,Wu R,Huang C,Ma X,Geng S,Wu J,Zhong C
Sun Jan 01 00:00:00 UTC 2017
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Biochemical and biophysical research communications
Wang D,Kong X,Li Y,Qian W,Ma J,Wang D,Yu D,Zhong C
Sat Nov 04 00:00:00 UTC 2017
Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway.
Biochemical and biophysical research communications
Wang D,Kong X,Li Y,Qian W,Ma J,Wang D,Yu D,Zhong C
Sat Nov 04 00:00:00 UTC 2017
Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide.
Biotechnology and applied biochemistry
Tan MJ,Cao XW,Li PF,Zhai YZ,Zhou Y,Liu YJ,Zhao J,Wang FJ
Wed Nov 01 00:00:00 UTC 2017
Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide.
Biotechnology and applied biochemistry
Tan MJ,Cao XW,Li PF,Zhai YZ,Zhou Y,Liu YJ,Zhao J,Wang FJ
Wed Nov 01 00:00:00 UTC 2017
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Scientific reports
Huang T,Xiao Y,Yi L,Li L,Wang M,Tian C,Ma H,He K,Wang Y,Han B,Ye X,Li X
Mon Feb 06 00:00:00 UTC 2017
Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo.
Scientific reports
Huang T,Xiao Y,Yi L,Li L,Wang M,Tian C,Ma H,He K,Wang Y,Han B,Ye X,Li X
Mon Feb 06 00:00:00 UTC 2017
Protective Effects of Fucoidan on Aβ25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice.
Marine drugs
Wei H,Gao Z,Zheng L,Zhang C,Liu Z,Yang Y,Teng H,Hou L,Yin Y,Zou X
Thu Mar 16 00:00:00 UTC 2017
Protective Effects of Fucoidan on Aβ25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice.
Marine drugs
Wei H,Gao Z,Zheng L,Zhang C,Liu Z,Yang Y,Teng H,Hou L,Yin Y,Zou X
Thu Mar 16 00:00:00 UTC 2017
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
International immunopharmacology
Peng Z,Gong X,Yang Y,Huang L,Zhang Q,Zhang P,Wan R,Zhang B
Wed Nov 01 00:00:00 UTC 2017
ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats.
Cell death & disease
Zheng Q,Li Y,Zhang D,Cui X,Dai K,Yang Y,Liu S,Tan J,Yan Q
Thu Oct 26 00:00:00 UTC 2017
ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats.
Cell death & disease
Zheng Q,Li Y,Zhang D,Cui X,Dai K,Yang Y,Liu S,Tan J,Yan Q
Thu Oct 26 00:00:00 UTC 2017
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells.
Molecules (Basel, Switzerland)
Song L,Wang Z,Wang Y,Guo D,Yang J,Chen L,Tan N
Sat Nov 11 00:00:00 UTC 2017
Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells.
Molecules (Basel, Switzerland)
Song L,Wang Z,Wang Y,Guo D,Yang J,Chen L,Tan N
Sat Nov 11 00:00:00 UTC 2017
Epigallocatechin-3-gallate inhibits H2O2-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor.
Scientific reports
Yan X,Li Y,Yu H,Wang W,Wu C,Yang Y,Hu Y,Shi X,Li J
Thu Aug 10 00:00:00 UTC 2017
Epigallocatechin-3-gallate inhibits H2O2-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor.
Scientific reports
Yan X,Li Y,Yu H,Wang W,Wu C,Yang Y,Hu Y,Shi X,Li J
Thu Aug 10 00:00:00 UTC 2017
Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy.
Cell death & disease
Wu B,Cui J,Yang XM,Liu ZY,Song F,Li L,Jiang JL,Chen ZN
Thu Jul 13 00:00:00 UTC 2017
Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy.
Cell death & disease
Wu B,Cui J,Yang XM,Liu ZY,Song F,Li L,Jiang JL,Chen ZN
Thu Jul 13 00:00:00 UTC 2017
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Oncotarget
Yang Y,Gong XB,Huang LG,Wang ZX,Wan RZ,Zhang P,Zhang QY,Chen Z,Zhang BS
Tue May 09 00:00:00 UTC 2017
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Oncotarget
Yang Y,Gong XB,Huang LG,Wang ZX,Wan RZ,Zhang P,Zhang QY,Chen Z,Zhang BS
Tue May 09 00:00:00 UTC 2017
Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells.
Autophagy
Li X,Zhu F,Jiang J,Sun C,Zhong Q,Shen M,Wang X,Tian R,Shi C,Xu M,Peng F,Guo X,Hu J,Ye D,Wang M,Qin R
Thu Sep 01 00:00:00 UTC 2016
Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells.
Autophagy
Li X,Zhu F,Jiang J,Sun C,Zhong Q,Shen M,Wang X,Tian R,Shi C,Xu M,Peng F,Guo X,Hu J,Ye D,Wang M,Qin R
Thu Sep 01 00:00:00 UTC 2016
Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Tang Q,Ji F,Sun W,Wang J,Guo J,Guo L,Li Y,Bao Y
Thu Dec 15 00:00:00 UTC 2016
Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Tang Q,Ji F,Sun W,Wang J,Guo J,Guo L,Li Y,Bao Y
Thu Dec 15 00:00:00 UTC 2016
Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhao L,Wen Q,Yang G,Huang Z,Shen T,Li H,Ren D
Mon Feb 15 00:00:00 UTC 2016
Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhao L,Wen Q,Yang G,Huang Z,Shen T,Li H,Ren D
Mon Feb 15 00:00:00 UTC 2016
Poly C binding protein 1 represses autophagy through downregulation of LC3B to promote tumor cell apoptosis in starvation.
The international journal of biochemistry & cell biology
Zhang W,Shi H,Zhang M,Liu B,Mao S,Li L,Tong F,Liu G,Yang S,Wang H
Fri Apr 01 00:00:00 UTC 2016
Poly C binding protein 1 represses autophagy through downregulation of LC3B to promote tumor cell apoptosis in starvation.
The international journal of biochemistry & cell biology
Zhang W,Shi H,Zhang M,Liu B,Mao S,Li L,Tong F,Liu G,Yang S,Wang H
Fri Apr 01 00:00:00 UTC 2016
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Cell cycle (Georgetown, Tex.)
Yuan S,Wen J,Cheng J,Shen W,Zhou S,Yan W,Shen L,Luo A,Wang S
Tue Nov 01 00:00:00 UTC 2016
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Cell cycle (Georgetown, Tex.)
Yuan S,Wen J,Cheng J,Shen W,Zhou S,Yan W,Shen L,Luo A,Wang S
Tue Nov 01 00:00:00 UTC 2016
Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells.
Molecular carcinogenesis
Liu W,Ning R,Chen RN,Huang XF,Dai QS,Hu JH,Wang YW,Wu LL,Xiong J,Hu G,Guo QL,Yang J,Wang H
Sun May 01 00:00:00 UTC 2016
Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells.
Molecular carcinogenesis
Liu W,Ning R,Chen RN,Huang XF,Dai QS,Hu JH,Wang YW,Wu LL,Xiong J,Hu G,Guo QL,Yang J,Wang H
Sun May 01 00:00:00 UTC 2016
Resveratrol Increases Anti-Proliferative Activity of Bestatin Through Downregulating P-Glycoprotein Expression Via Inhibiting PI3K/Akt/mTOR Pathway in K562/ADR Cells.
Journal of cellular biochemistry
Wang L,Wang C,Jia Y,Liu Z,Shu X,Liu K
Sun May 01 00:00:00 UTC 2016
Resveratrol Increases Anti-Proliferative Activity of Bestatin Through Downregulating P-Glycoprotein Expression Via Inhibiting PI3K/Akt/mTOR Pathway in K562/ADR Cells.
Journal of cellular biochemistry
Wang L,Wang C,Jia Y,Liu Z,Shu X,Liu K
Sun May 01 00:00:00 UTC 2016
Protective effects of Forsythia suspense extract with antioxidant and anti-inflammatory properties in a model of rotenone induced neurotoxicity.
Neurotoxicology
Zhang S,Shao SY,Song XY,Xia CY,Yang YN,Zhang PC,Chen NH
Fri Jan 01 00:00:00 UTC 2016
Protective effects of Forsythia suspense extract with antioxidant and anti-inflammatory properties in a model of rotenone induced neurotoxicity.
Neurotoxicology
Zhang S,Shao SY,Song XY,Xia CY,Yang YN,Zhang PC,Chen NH
Fri Jan 01 00:00:00 UTC 2016
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Biology of reproduction
Nie D,Zhang D,Dai J,Zhang M,Zhao X,Xu W,Chen Z,Wang L,Wang Z,Qiao Z
Mon Feb 01 00:00:00 UTC 2016
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Biology of reproduction
Nie D,Zhang D,Dai J,Zhang M,Zhao X,Xu W,Chen Z,Wang L,Wang Z,Qiao Z
Mon Feb 01 00:00:00 UTC 2016
Activating Transcription Factor 4 (ATF4)-ATF3-C/EBP Homologous Protein (CHOP) Cascade Shows an Essential Role in the ER Stress-Induced Sensitization of Tetrachlorobenzoquinone-Challenged PC12 Cells to ROS-Mediated Apoptosis via Death Receptor 5 (DR5) Signaling.
Chemical research in toxicology
Liu Z,Shi Q,Song X,Wang Y,Wang Y,Song E,Song Y
Mon Sep 19 00:00:00 UTC 2016
Activating Transcription Factor 4 (ATF4)-ATF3-C/EBP Homologous Protein (CHOP) Cascade Shows an Essential Role in the ER Stress-Induced Sensitization of Tetrachlorobenzoquinone-Challenged PC12 Cells to ROS-Mediated Apoptosis via Death Receptor 5 (DR5) Signaling.
Chemical research in toxicology
Liu Z,Shi Q,Song X,Wang Y,Wang Y,Song E,Song Y
Mon Sep 19 00:00:00 UTC 2016
Activating Transcription Factor 4 (ATF4)-ATF3-C/EBP Homologous Protein (CHOP) Cascade Shows an Essential Role in the ER Stress-Induced Sensitization of Tetrachlorobenzoquinone-Challenged PC12 Cells to ROS-Mediated Apoptosis via Death Receptor 5 (DR5) Signaling.
Chemical research in toxicology
Liu Z,Shi Q,Song X,Wang Y,Wang Y,Song E,Song Y
Mon Sep 19 00:00:00 UTC 2016
Activating Transcription Factor 4 (ATF4)-ATF3-C/EBP Homologous Protein (CHOP) Cascade Shows an Essential Role in the ER Stress-Induced Sensitization of Tetrachlorobenzoquinone-Challenged PC12 Cells to ROS-Mediated Apoptosis via Death Receptor 5 (DR5) Signaling.
Chemical research in toxicology
Liu Z,Shi Q,Song X,Wang Y,Wang Y,Song E,Song Y
Mon Sep 19 00:00:00 UTC 2016
Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.
Toxicology in vitro : an international journal published in association with BIBRA
Aziz F,Wang X,Liu J,Yan Q
Tue Mar 01 00:00:00 UTC 2016
Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.
Toxicology in vitro : an international journal published in association with BIBRA
Aziz F,Wang X,Liu J,Yan Q
Tue Mar 01 00:00:00 UTC 2016
Enhanced anti-tumor activity of trichosanthin after combination with a human-derived cell-penetrating peptide, and a possible mechanism of activity.
Fitoterapia
Lu YZ,Li PF,Li YZ,Luo F,Guo C,Lin B,Cao XW,Zhao J,Wang FJ
Fri Jul 01 00:00:00 UTC 2016
Enhanced anti-tumor activity of trichosanthin after combination with a human-derived cell-penetrating peptide, and a possible mechanism of activity.
Fitoterapia
Lu YZ,Li PF,Li YZ,Luo F,Guo C,Lin B,Cao XW,Zhao J,Wang FJ
Fri Jul 01 00:00:00 UTC 2016
Hsp70 suppresses apoptosis of BRL cells by regulating the expression of Bcl-2, cytochrome C, and caspase 8/3.
In vitro cellular & developmental biology. Animal
Kong F,Wang H,Guo J,Peng M,Ji H,Yang H,Liu B,Wang J,Zhang X,Li S
Sun May 01 00:00:00 UTC 2016
Hsp70 suppresses apoptosis of BRL cells by regulating the expression of Bcl-2, cytochrome C, and caspase 8/3.
In vitro cellular & developmental biology. Animal
Kong F,Wang H,Guo J,Peng M,Ji H,Yang H,Liu B,Wang J,Zhang X,Li S
Sun May 01 00:00:00 UTC 2016
Ethylacetate extract from Tetrastigma hemsleyanum induces apoptosis via the mitochondrial caspase-dependent intrinsic pathway in HepG2 cells.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Peng X,Zhang YY,Wang J,Ji Q
Fri Jan 01 00:00:00 UTC 2016
Ethylacetate extract from Tetrastigma hemsleyanum induces apoptosis via the mitochondrial caspase-dependent intrinsic pathway in HepG2 cells.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Peng X,Zhang YY,Wang J,Ji Q
Fri Jan 01 00:00:00 UTC 2016
Hyperthermotherapy enhances antitumor effect of 5-aminolevulinic acid-mediated sonodynamic therapy with activation of caspase-dependent apoptotic pathway in human glioma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Ju D,Yamaguchi F,Zhan G,Higuchi T,Asakura T,Morita A,Orimo H,Hu S
Mon Aug 01 00:00:00 UTC 2016
Hyperthermotherapy enhances antitumor effect of 5-aminolevulinic acid-mediated sonodynamic therapy with activation of caspase-dependent apoptotic pathway in human glioma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Ju D,Yamaguchi F,Zhan G,Higuchi T,Asakura T,Morita A,Orimo H,Hu S
Mon Aug 01 00:00:00 UTC 2016
DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways.
Scientific reports
Zou M,Duan Y,Wang P,Gao R,Chen X,Ou Y,Liang M,Wang Z,Yuan Y,Wang L,Zhu H
Thu Jun 02 00:00:00 UTC 2016
DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways.
Scientific reports
Zou M,Duan Y,Wang P,Gao R,Chen X,Ou Y,Liang M,Wang Z,Yuan Y,Wang L,Zhu H
Thu Jun 02 00:00:00 UTC 2016
Interferon α Induces the Apoptosis of Cervical Cancer HeLa Cells by Activating both the Intrinsic Mitochondrial Pathway and Endoplasmic Reticulum Stress-Induced Pathway.
International journal of molecular sciences
Shi WY,Cao C,Liu L
Wed Nov 02 00:00:00 UTC 2016
Interferon α Induces the Apoptosis of Cervical Cancer HeLa Cells by Activating both the Intrinsic Mitochondrial Pathway and Endoplasmic Reticulum Stress-Induced Pathway.
International journal of molecular sciences
Shi WY,Cao C,Liu L
Wed Nov 02 00:00:00 UTC 2016
Mycobacterium bovis Induces Endoplasmic Reticulum Stress Mediated-Apoptosis by Activating IRF3 in a Murine Macrophage Cell Line.
Frontiers in cellular and infection microbiology
Cui Y,Zhao D,Sreevatsan S,Liu C,Yang W,Song Z,Yang L,Barrow P,Zhou X
Thu Sep 21 00:00:00 UTC 2017
Mycobacterium bovis Induces Endoplasmic Reticulum Stress Mediated-Apoptosis by Activating IRF3 in a Murine Macrophage Cell Line.
Frontiers in cellular and infection microbiology
Cui Y,Zhao D,Sreevatsan S,Liu C,Yang W,Song Z,Yang L,Barrow P,Zhou X
Thu Sep 21 00:00:00 UTC 2017
Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells.
Cancer letters
Li X,Zhu F,Jiang J,Sun C,Wang X,Shen M,Tian R,Shi C,Xu M,Peng F,Guo X,Wang M,Qin R
Sun Feb 01 00:00:00 UTC 2015
Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells.
Cancer letters
Li X,Zhu F,Jiang J,Sun C,Wang X,Shen M,Tian R,Shi C,Xu M,Peng F,Guo X,Wang M,Qin R
Sun Feb 01 00:00:00 UTC 2015
Down-regulated expression of Annexin A7 induces apoptosis in mouse hepatocarcinoma cell line by the intrinsic mitochondrial pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Huang Y,Du Y,Zhang X,Bai L,Mibrahim M,Zhang J,Wei Y,Li C,Fan S,Wang H,Zhao Z,Tang J
Sun Mar 01 00:00:00 UTC 2015
Down-regulated expression of Annexin A7 induces apoptosis in mouse hepatocarcinoma cell line by the intrinsic mitochondrial pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Huang Y,Du Y,Zhang X,Bai L,Mibrahim M,Zhang J,Wei Y,Li C,Fan S,Wang H,Zhao Z,Tang J
Sun Mar 01 00:00:00 UTC 2015
Curcumin combined with oxaliplatin effectively suppress colorectal carcinoma in vivo through inducing apoptosis.
Phytotherapy research : PTR
Guo LD,Shen YQ,Zhao XH,Guo LJ,Yu ZJ,Wang D,Liu LM,Liu JZ
Sun Mar 01 00:00:00 UTC 2015
Curcumin combined with oxaliplatin effectively suppress colorectal carcinoma in vivo through inducing apoptosis.
Phytotherapy research : PTR
Guo LD,Shen YQ,Zhao XH,Guo LJ,Yu ZJ,Wang D,Liu LM,Liu JZ
Sun Mar 01 00:00:00 UTC 2015
Effects of the total saponins from Dioscorea nipponica on immunoregulation in aplastic anemia mice.
The American journal of Chinese medicine
Wang Y,Yan T,Ma L,Liu B
Thu Jan 14 00:00:00 UTC 2016
Effects of the total saponins from Dioscorea nipponica on immunoregulation in aplastic anemia mice.
The American journal of Chinese medicine
Wang Y,Yan T,Ma L,Liu B
Thu Jan 14 00:00:00 UTC 2016
Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells.
Neurotoxicology
Hu L,Su C,Song X,Shi Q,Fu J,Xia X,Xu D,Song E,Song Y
Wed Jul 01 00:00:00 UTC 2015
Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells.
Neurotoxicology
Hu L,Su C,Song X,Shi Q,Fu J,Xia X,Xu D,Song E,Song Y
Wed Jul 01 00:00:00 UTC 2015
Inhibitive effects of 15-deoxy-Δ(12),(14)-prostaglandin J2 on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis.
OncoTargets and therapy
Chen K,Dai W,Wang F,Xia Y,Li J,Li S,Liu T,Zhang R,Wang J,Lu W,Zhou Y,Yin Q,Zheng Y,Abudumijiti H,Chen R,Lu J,Zhou Y,Guo C
Tue Dec 15 00:00:00 UTC 2015
Inhibitive effects of 15-deoxy-Δ(12),(14)-prostaglandin J2 on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis.
OncoTargets and therapy
Chen K,Dai W,Wang F,Xia Y,Li J,Li S,Liu T,Zhang R,Wang J,Lu W,Zhou Y,Yin Q,Zheng Y,Abudumijiti H,Chen R,Lu J,Zhou Y,Guo C
Tue Dec 15 00:00:00 UTC 2015
Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells.
Chemical research in toxicology
Song X,Li L,Shi Q,Lehmler HJ,Fu J,Su C,Xia X,Song E,Song Y
Mon Nov 16 00:00:00 UTC 2015
Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells.
Chemical research in toxicology
Song X,Li L,Shi Q,Lehmler HJ,Fu J,Su C,Xia X,Song E,Song Y
Mon Nov 16 00:00:00 UTC 2015
Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line.
Thoracic cancer
Zhang X,Jiang SJ,Shang B,Jiang HJ
Sun Mar 01 00:00:00 UTC 2015
Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line.
Thoracic cancer
Zhang X,Jiang SJ,Shang B,Jiang HJ
Sun Mar 01 00:00:00 UTC 2015
CXCR1/2 antagonism with CXCL8/Interleukin-8 analogue CXCL8(3-72)K11R/G31P restricts lung cancer growth by inhibiting tumor cell proliferation and suppressing angiogenesis.
Oncotarget
Khan MN,Wang B,Wei J,Zhang Y,Li Q,Luan X,Cheng JW,Gordon JR,Li F,Liu H
Fri Aug 28 00:00:00 UTC 2015
CXCR1/2 antagonism with CXCL8/Interleukin-8 analogue CXCL8(3-72)K11R/G31P restricts lung cancer growth by inhibiting tumor cell proliferation and suppressing angiogenesis.
Oncotarget
Khan MN,Wang B,Wei J,Zhang Y,Li Q,Luan X,Cheng JW,Gordon JR,Li F,Liu H
Fri Aug 28 00:00:00 UTC 2015
Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice.
Drug design, development and therapy
Mao Y,Wang J,Yu F,Cheng J,Li H,Guo C,Fan X
Wed Jul 06 00:00:00 UTC 2016
Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice.
Drug design, development and therapy
Mao Y,Wang J,Yu F,Cheng J,Li H,Guo C,Fan X
Wed Jul 06 00:00:00 UTC 2016
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
International immunopharmacology
Xia X,Su C,Fu J,Zhang P,Jiang X,Xu D,Hu L,Song E,Song Y
Wed Oct 01 00:00:00 UTC 2014
Role of α-lipoic acid in LPS/d-GalN induced fulminant hepatic failure in mice: studies on oxidative stress, inflammation and apoptosis.
International immunopharmacology
Xia X,Su C,Fu J,Zhang P,Jiang X,Xu D,Hu L,Song E,Song Y
Wed Oct 01 00:00:00 UTC 2014
Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro.
Chemico-biological interactions
Hu L,Li L,Xu D,Xia X,Pi R,Xu D,Wang W,Du H,Song E,Song Y
Fri Apr 25 00:00:00 UTC 2014
Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro.
Chemico-biological interactions
Hu L,Li L,Xu D,Xia X,Pi R,Xu D,Wang W,Du H,Song E,Song Y
Fri Apr 25 00:00:00 UTC 2014
Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
Wu J,Chen W,Yin Y,Zheng Z,Zou G
Sun Jun 01 00:00:00 UTC 2014
Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
Wu J,Chen W,Yin Y,Zheng Z,Zou G
Sun Jun 01 00:00:00 UTC 2014
Emodin regulates apoptotic pathway in human liver cancer cells.
Phytotherapy research : PTR
Yu JQ,Bao W,Lei JC
Fri Feb 01 00:00:00 UTC 2013
Emodin regulates apoptotic pathway in human liver cancer cells.
Phytotherapy research : PTR
Yu JQ,Bao W,Lei JC
Fri Feb 01 00:00:00 UTC 2013
Khat (Catha edulis) generates reactive oxygen species and promotes hepatic cell apoptosis via MAPK activation.
International journal of molecular medicine
Abid MD,Chen J,Xiang M,Zhou J,Chen X,Gong F
Thu Aug 01 00:00:00 UTC 2013
Khat (Catha edulis) generates reactive oxygen species and promotes hepatic cell apoptosis via MAPK activation.
International journal of molecular medicine
Abid MD,Chen J,Xiang M,Zhou J,Chen X,Gong F
Thu Aug 01 00:00:00 UTC 2013
Induction of apoptosis in infantile hemangioma endothelial cells by propranolol.
Experimental and therapeutic medicine
Tu JB,Ma RZ,Dong Q,Jiang F,Hu XY,Li QY,Pattar P,Zhang H
Thu Aug 01 00:00:00 UTC 2013
Induction of apoptosis in infantile hemangioma endothelial cells by propranolol.
Experimental and therapeutic medicine
Tu JB,Ma RZ,Dong Q,Jiang F,Hu XY,Li QY,Pattar P,Zhang H
Thu Aug 01 00:00:00 UTC 2013
Alantolactone induces activation of apoptosis in human hepatoma cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Lei JC,Yu JQ,Yin Y,Liu YW,Zou GL
Sat Sep 01 00:00:00 UTC 2012
Alantolactone induces activation of apoptosis in human hepatoma cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Lei JC,Yu JQ,Yin Y,Liu YW,Zou GL
Sat Sep 01 00:00:00 UTC 2012
Proteomic analysis of mitochondria from infantile hemangioma endothelial cells treated with sodium morrhuate and its liposomal formulation.
Journal of biochemical and molecular toxicology
Tu JB,Dong Q,Hu XY,Jiang F,Ma RZ,He LY,Yang ZQ
Sat Sep 01 00:00:00 UTC 2012
Proteomic analysis of mitochondria from infantile hemangioma endothelial cells treated with sodium morrhuate and its liposomal formulation.
Journal of biochemical and molecular toxicology
Tu JB,Dong Q,Hu XY,Jiang F,Ma RZ,He LY,Yang ZQ
Sat Sep 01 00:00:00 UTC 2012
NF-κB, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G₂/M cell cycle arrest.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yin Y,Chen W,Tang C,Ding H,Jang J,Weng M,Cai Y,Zou G
Thu Dec 01 00:00:00 UTC 2011
NF-κB, JNK and p53 pathways are involved in tubeimoside-1-induced apoptosis in HepG2 cells with oxidative stress and G₂/M cell cycle arrest.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yin Y,Chen W,Tang C,Ding H,Jang J,Weng M,Cai Y,Zou G
Thu Dec 01 00:00:00 UTC 2011
Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.
European journal of pharmacology
Liu H,Xiao Y,Xiong C,Wei A,Ruan J
Fri Mar 11 00:00:00 UTC 2011
Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.
European journal of pharmacology
Liu H,Xiao Y,Xiong C,Wei A,Ruan J
Fri Mar 11 00:00:00 UTC 2011
Characterization of 9-nitrocamptothecin liposomes: anticancer properties and mechanisms on hepatocellular carcinoma in vitro and in vivo.
PloS one
Zheng S,Chang S,Lu J,Chen Z,Xie L,Nie Y,He B,Zou S,Gu Z
Fri Oct 21 00:00:00 UTC 2011
Characterization of 9-nitrocamptothecin liposomes: anticancer properties and mechanisms on hepatocellular carcinoma in vitro and in vivo.
PloS one
Zheng S,Chang S,Lu J,Chen Z,Xie L,Nie Y,He B,Zou S,Gu Z
Fri Oct 21 00:00:00 UTC 2011
alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.
Biochemical pharmacology
Chen W,Hou J,Yin Y,Jang J,Zheng Z,Fan H,Zou G
Thu Jul 15 00:00:00 UTC 2010
alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.
Biochemical pharmacology
Chen W,Hou J,Yin Y,Jang J,Zheng Z,Fan H,Zou G
Thu Jul 15 00:00:00 UTC 2010
