Hamburger Menu Button
Thermo Fisher Scientific Logo
登入
還沒有帳戶嗎 ? 立即註冊
  • 產品
    • Antibodies
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • Cell Culture Media
    • Chemicals
    • Western Blot Products
    • Chromatography Columns and Cartridges
    • Lab Equipment
    • Lab Plasticware and Supplies
    • Microplates
    • Greener Products
    • 查看所有產品類別
  • 應用
    • 生物製程
    • 細胞培養和轉染
    • 食品和飲料
    • 實驗室解決方案
    • 製藥和生物製藥
    • 即時定量PCR
    • 半導體分析
    • 臨床和診斷
    • 數位解決方案
    • 分子光譜、同位素與元素分析
    • 查看所有應用與技術
  • 服務
    • 360° CDMO 和 CRO 服務
    • CDMO 服务
    • 临床试验 CRO 服务
    • 客製化服務
    • 企業服務
    • 金融與租賃服務
    • 儀器服務
    • 實驗室資訊學
    • 授權與商業供應
    • 培訓服務
    • 查看所有服務
  • 支援
    • 線上訂購協助
    • 數位解決方案
    • 產品支持
    • 技術相關資訊
    • 培訓與教育
    • 查看所有協助與支援
  • 熱門商品
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • 特價商品
  • 聯絡我們
  • 快速訂購
  • 訂單狀態與貨物追蹤
  • 文件和證書
Thermo Fisher Scientific Logo

Search

Search All
Search button
          • 訂單查詢
          • 快速訂購
          • 登入
            登入
            還沒有帳戶嗎 ? 立即註冊
            • 帳戶
            • 訂單
            • Connect: Lab, Data, Apps
            • 客製化產品與項目
            • 儀器管理

          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Caveolin 1 Antibodies

          Invitrogen

          Caveolin 1 Polyclonal Antibody

          Advanced Verification
          8 Published Figures
          20 References
          View all (47) Caveolin 1 antibodies

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Protocols
          Questions & Answers
          Tech Support

          Cite Caveolin 1 Polyclonal Antibody

          • Antibody Testing Data (5)
          • Published Figures (8)
          • Advanced Verification (4)
          Caveolin 1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          Caveolin 1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 17

          {{ $ctrl.currentElement.advancedVerification.fullName }}
          {{ $ctrl.currentElement.advancedVerification.text }}

          Caveolin 1 Antibody (PA1-064) in ICC/IF

          Immunofluorescence analysis of Caveolin 1 was done on 70% confluent log phase A-375 cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.25% Triton™ X-100 for 10 minutes, and blocked with 5% BSA for 1 hour at room temperature. The cells were labeled with Caveolin 1 Rabbit Polyclonal Antibody (Product # PA1-064) at 1 µg/mL in 1% BSA and incubated for 3 hours at room tempe... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

          {{$ctrl.videoDesc}}

          {{$ctrl.videoLongDesc}}

          Caveolin 1 Antibody in Immunocytochemistry (ICC/IF)
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody in Immunoprecipitation (IP)
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody in Western Blot, Immunocytochemistry, Immunoprecipitation (WB, ICC/IF, IP)
          Caveolin 1 Antibody in Immunocytochemistry (ICC/IF)
          Caveolin 1 Antibody in Immunohistochemistry (IHC)
          Caveolin 1 Antibody in Immunohistochemistry (IHC)
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody in Western Blot (WB)
          Caveolin 1 Antibody
          Caveolin 1 Antibody
          Caveolin 1 Antibody
          Caveolin 1 Antibody
          Caveolin 1 Polyclonal Antibody

          Product Details

          PA1-064

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-2 µg/mL
          View 11 publications 11 publications

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          1-2 µg/mL
          View 6 publications 6 publications

          Immunoprecipitation (IP)

          5 µg
          View 1 publication 1 publication

          Affinity Purification (AP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Dog, Hamster, Human, Mouse, Rat

          Published species

          C. elegans, Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide corresponding to residues M(1) S G G K Y V D S E G H L Y T V P(17) C of human CAV1.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS with 1mg/mL BSA

          Contains

          0.05% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2072027

          Product Specific Information

          PA1-064 detects caveolin 1 from human, canine, hamster, mouse, and rat tissues and cells.

          PA1-064 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects an ~22 kDa protein representing caveolin 1 from rat heart protein extract.

          The PA1-064 immunogen is a synthetic peptide corresponding to residues M(1) S G G K Y V D S E G H L Y T V P(17) C of human CAV1. This sequence is completely conserved between human, mouse, canine, bovine, and rat. The PA1-064 immunizing peptide (Cat. # PEP-146) is available for use in neutralization and control experiments.

          Target Information

          Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: caveolae; caveolin 1, caveolae protein, 22kDa; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; Caveolin-1; cell growth-inhibiting protein 32; HGNC:1527; OTTHUMP00000196475; Vesicular integral-membrane protein VIP21

          View more View less

          Gene Aliases: BSCL3; CAV; Cav-1; CAV1; Caveolin-1; CGL3; LCCNS; MSTP085; PPH3; VIP21

          View more View less

          UniProt ID: (Dog) P33724, (Human) Q03135, (Mouse) P49817

          View more View less

          Entrez Gene ID: (Dog) 403980, (Human) 857, (Mouse) 12389, (Rat) 25404, (Chinese hamster) 100753021

          View more View less

          Function(s)
          receptor binding protein binding peptidase activator activity protein binding, bridging identical protein binding macromolecular complex binding protein heterodimerization activity Rac GTPase binding nitric-oxide synthase binding ATPase binding inward rectifier potassium channel inhibitor activity RNA polymerase I transcription factor binding patched binding structural molecule activity cholesterol binding enzyme binding protein kinase binding syntaxin binding protein complex scaffold ion channel binding MDM2/MDM4 family protein binding SNARE binding kinase binding scaffold/adaptor protein
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter inactivation of MAPK activity angiogenesis vasculogenesis response to hypoxia negative regulation of cytokine-mediated signaling pathway response to ischemia regulation of the force of heart contraction by chemical signal triglyceride metabolic process calcium ion transport regulation of smooth muscle contraction skeletal muscle tissue development lactation response to bacterium positive regulation of calcium ion transport into cytosol posttranscriptional regulation of gene expression positive regulation of gene expression positive regulation of cholesterol efflux positive regulation of peptidase activity vesicle organization receptor-mediated endocytosis of virus by host cell regulation of fatty acid metabolic process lipid storage regulation of blood coagulation positive regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of epithelial cell differentiation T cell costimulation negative regulation of protein ubiquitination positive regulation of protein ubiquitination receptor internalization negative regulation of protein binding positive regulation of protein binding response to progesterone negative regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation nitric oxide homeostasis positive regulation of toll-like receptor 3 signaling pathway insulin receptor internalization vasoconstriction negative regulation of tyrosine phosphorylation of STAT protein cholesterol homeostasis response to estrogen protein localization to plasma membrane raft negative regulation of nitric oxide biosynthetic process positive regulation of vasoconstriction negative regulation of pinocytosis negative regulation of nitric-oxide synthase activity positive regulation of NF-kappaB transcription factor activity response to calcium ion membrane depolarization mammary gland involution positive regulation of cell adhesion molecule production negative regulation of necroptotic process caveola assembly cellular response to exogenous dsRNA cellular response to hyperoxia cellular response to transforming growth factor beta stimulus basement membrane organization caveolin-mediated endocytosis regulation of heart rate by cardiac conduction angiotensin-activated signaling pathway involved in heart process negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway apoptotic signaling pathway regulation of membrane repolarization during action potential regulation of ventricular cardiac muscle cell action potential positive regulation of cold-induced thermogenesis regulation of ruffle assembly negative regulation of peptidyl-tyrosine autophosphorylation regulation of cell communication by electrical coupling involved in cardiac conduction positive regulation of ER-associated ubiquitin-dependent protein catabolic process protein localization to basolateral plasma membrane positive regulation of gap junction assembly negative regulation of inward rectifier potassium channel activity receptor internalization involved in canonical Wnt signaling pathway regulation of entry of bacterium into host cell negative regulation of anoikis positive regulation of extrinsic apoptotic signaling pathway positive regulation of intrinsic apoptotic signaling pathway MAPK cascade negative regulation of endothelial cell proliferation positive regulation of endothelial cell proliferation cellular calcium ion homeostasis response to nutrient protein localization response to gamma radiation negative regulation of muscle cell apoptotic process cholesterol transport mammary gland development organ regeneration positive regulation of microtubule polymerization maintenance of protein location in cell cholesterol efflux wound healing response to drug negative regulation of tyrosine phosphorylation of Stat5 protein positive regulation of catalytic activity negative regulation of MAPK cascade negative regulation of neuron differentiation positive regulation of endocytosis negative regulation of JAK-STAT cascade microtubule polymerization negative regulation of smooth muscle cell proliferation leukocyte migration regulation of nitric-oxide synthase activity protein homooligomerization response to glucocorticoid regulation of cytosolic calcium ion concentration regulation of peptidase activity calcium ion homeostasis negative regulation of protein tyrosine kinase activity negative regulation of ERK1 and ERK2 cascade cellular response to mechanical stimulus cellular response to peptide hormone stimulus cellular senescence regulation of cardiac muscle cell action potential involved in regulation of contraction negative regulation of potassium ion transmembrane transport regulation of inward rectifier potassium channel activity beta-catenin destruction complex disassembly negative regulation of cation channel activity regulation of the force of heart contraction endocytosis negative regulation of cell proliferation response to mechanical stimulus positive regulation of signal transduction negative regulation of signal transduction negative regulation of BMP signaling pathway negative regulation of MAP kinase activity protein oligomerization cellular response to starvation
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          產品訂購 Plus Icon Minus Icon
          • 訂單狀態
          • 訂購協助
          • 快速訂購
          • 現貨供應中心
          • 電子採購
          支持 Plus Icon Minus Icon
          • 協助與支持
          • 聯絡我們
          • 技術支持中心
          • 搜尋文件和證書
          • 回報網站問題
          資源 Plus Icon Minus Icon
          • 學習中心
          • 促銷活動
          • 活動和網路研討會
          • 社群媒體
          關於 Thermo Fisher Plus Icon Minus Icon
          • 關於我們 關於我們
          • 人才招募 人才招募
          • 投資者資訊 投資者資訊
          • 新聞 新聞
          • 企業社會責任 企業社會責任
          • 商標
          • 政策和聲明
          品牌 Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Policy
          • Price & Freight Policy
          © 2006-2026 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          Taiwan flag icon
          Taiwan

          Your items have has been added!


          Host server : magellan-search-green-55658555d6-7l2qm:80/100.66.75.127:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline