This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
This antibody is predicted to react with bovine, canine and porcine based on sequence homology.
Caveolin-3 (CAV3) acts as a scaffolding protein within the caveolar membrane. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-3 may also regulate voltage-gated potassium channels. It also plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Caveolin-3 also mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae. Mutations in the gene can result in HyperCKmia, rippling muscle disease 2, cardiomyopathy, long QT syndrome 9, sudden infant death syndrome, and myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAV; Caveolin-3; M-caveolin; MGC126100; MGC126101; MGC126129; structural protein
Gene Aliases: AI385751; Cav-3; CAV3; LGMD1C; LQT9; M-cav; VIP-21; VIP21
Molecular Function: scaffold/adaptor protein