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Immunogen sequence: QQQNQHQQPT APPQQAAAPP QAPPPQQNST QTNGTAGGAG AGVGGTGAGL QHSQDSSLNQ VPPNKKPRLG PSGANSGGPV MPSDYQHSSS RLNYQSSVQG S; Positive Samples: DU145, U-87MG, A-549, HeLa
CDC2L6 is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
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Protein Aliases: CDC2-related protein kinase 6; CDK8-like cyclin-dependent kinase; cell division cycle 2-like 6 (CDK8-like); Cell division cycle 2-like protein kinase 6; Cell division protein kinase 19; cyclin dependent kinase 19 variant 2; cyclin-dependent kinase (CDC2-like) 11; Cyclin-dependent kinase 11; Cyclin-dependent kinase 19; Death-preventing kinase
Gene Aliases: 2700084L06Rik; AI845279; AW228747; bA346C16.3; CDC2L6; CDK11; CDK19; KIAA1028; mKIAA1028
UniProt ID: (Human) Q9BWU1, (Mouse) Q8BWD8
Entrez Gene ID: (Human) 23097, (Mouse) 78334, (Rat) 309804
Molecular Function: non-receptor serine/threonine protein kinase
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