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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CDC40 Antibodies

          Invitrogen

          Cdc40 Polyclonal Antibody

          View all (11) CDC40 antibodies

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          Cite Cdc40 Polyclonal Antibody

          • Antibody Testing Data (1)
          Cdc40 Antibody in Immunocytochemistry (ICC/IF)
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          Cdc40 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          Cdc40 Antibody (PA5-65451) in ICC/IF

          Immunofluorescent staining of Cdc40 in human cell line U-251 MG shows localization to nucleoplasm. Samples were probed using a Cdc40 Polyclonal Antibody (Product # PA5-65451). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Cdc40 Antibody in Immunocytochemistry (ICC/IF)
          Cdc40 Polyclonal Antibody

          Product Details

          PA5-65451

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human Cdc40. Recombinant protein control fragment (Product #RP-106131).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2662169

          Product Specific Information

          Immunogen sequence: VQYNPTYETMF APEFGPENPF RTQQMAAPRN MLSGYAEPAH INDFMFEQQR RTFATYGYAL DPSLDNHQVS AKYIGSVEEA EKNQGLTVFE TGQKKT

          Highest antigen sequence identity to the following orthologs - mouse 100%, rat 73%.

          Target Information

          Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Cell division cycle 40 homolog; EH-binding protein 3; Ehb3; hPRP17; pre-mRNA splicing factor 17; Pre-mRNA-processing factor 17; PRP17 homolog

          View more View less

          Gene Aliases: CDC40; EHB3; PRP17; PRPF17

          View more View less

          UniProt ID: (Human) O60508

          View more View less

          Entrez Gene ID: (Human) 51362

          View more View less

          Function(s)
          second spliceosomal transesterification activity protein binding poly(A) RNA binding RNA metabolism protein RNA processing factor RNA splicing factor nucleic acid metabolism protein
          Process(es)
          generation of catalytic spliceosome for second transesterification step mRNA splicing, via spliceosome termination of RNA polymerase II transcription RNA export from nucleus mRNA export from nucleus RNA splicing mRNA 3'-end processing
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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