Keep as concentrated solution.
Positive Control: Mouse brain, PC-12, Rat2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This protein is a small GTPase of the Rho subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis, and cell progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42 1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrick syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in at least two transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 25kD antibody; 25kD)) antibody; 25kDa) antibody; CDC42 antibody; CDC42Hs antibody; Cell division control protein 42 homolog; cell division control protein 42 homolog antibody; cell division cycle 42 (GTP binding protein; cell division cycle 42 (GTP binding protein); cell division cycle 42 homolog; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein; dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein; G25K antibody; G25K GTP-binding protein; G25K GTP-binding protein antibody; growth-regulating protein antibody; small GTP binding protein CDC42 antibody
Gene Aliases: AI747189; AU018915; Cdc42