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This antibody detects endogenous protein at a molecular weight of 23 kDa.
Purity is >95% by SDS-PAGE.
Cdc42, a small GTPase, regulates Actin polymerization, elongation of cell shape and cell signaling through interactions with many different downstream effector proteins, most of which contain a Cdc42-binding motif known as a CRIB domain. Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein that localizes to both the cytoplasm and the cytoskeleton and contains one CRIB domain. Highly expressed in heart and present at lower levels in liver and pancreas, Cdc42EP2 interacts with Cdc42 and is thought to be involved in the organization of the Actin cytoskeleton and may also influence Actin filament assembly and overall cell shape.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Binder of Rho GTPases 1; CDC42 effector protein (Rho GTPase binding) 2; Cdc42 effector protein 2; CRIB-containing BOGR1 protein
Gene Aliases: 1110008C05Rik; BORG1; CDC42EP2; CEP2; D19Bwg1013e
UniProt ID: (Human) O14613, (Mouse) Q8JZX9, (Rat) Q5PQP4
Entrez Gene ID: (Human) 10435, (Mouse) 104252, (Rat) 309175
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