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Invitrogen
Cdc5L Polyclonal Antibody
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Product Details
PA5-114997
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CDC5L(Accession Q99459), corresponding to amino acid residues G207-G257.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CDC5L.
Target Information
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDC5 cell division cycle 5-like; Cdc5-like protein; Cdc5-related protein; Cell division cycle 5-like protein; cell division cycle 5-related protein; dJ319D22.1 (CDC5-like protein); hCDC5; KIAA0432; Pombe Cdc5-related protein; unnamed protein product
Gene Aliases: 1200002I02Rik; AA408004; CDC5; CDC5-LIKE; CDC5L; CEF1; dJ319D22.1; KIAA0432; PCDC5RP
UniProt ID: (Human) Q99459, (Rat) O08837, (Mouse) Q6A068
Entrez Gene ID: (Human) 988, (Rat) 85434, (Mouse) 71702
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
RNA binding
protein binding
protein domain specific binding
identical protein binding
WD40-repeat domain binding
chromatin binding
poly(A) RNA binding
G2/M transition of mitotic cell cycle
DNA repair
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
RNA splicing
signal transduction involved in DNA damage checkpoint
DNA damage checkpoint
mRNA splicing, via spliceosome
regulation of transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
positive regulation of transcription from RNA polymerase II promoter
cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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