Immunogen sequence: PPLTDLQKSE ELIKKEMITM LHYDLLHHPY EPSGNKKGKT VGFGTNNSEH ITYLEHNPYE KFSKEELKKA QDVLVQEMEV VKQGMSHGEL SSEAYNQVWE ECYSQVLYLP GQSRYTRANL ASKKDRIESL EKRLEINRGH MTTEAKRAAK MEKKMKILLG GYQSRAMGLM KQLNDLWDQI EQAHLELRTF EELKKHEDSA IPRRLECLKE DVQRQQEREK ELQHRYADLL LEKETLKSKF; Positive Samples: MCF7, THP-1, K-562, SW480, Mouse spleen, Mouse thymus, Mouse testis; Cellular Location: Cytoplasm, Nucleus, Nucleus speckle
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDC5 cell division cycle 5-like; Cdc5-like protein; Cdc5-related protein; Cell division cycle 5-like protein; cell division cycle 5-related protein; dJ319D22.1 (CDC5-like protein); Pombe cdc5-related protein
Gene Aliases: 1200002I02Rik; AA408004; CDC5; CDC5-LIKE; CDC5L; CEF1; dJ319D22.1; KIAA0432; PCDC5RP