This antibody is predicted to react with chicken, mouse and rat based on sequence homology.
CDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin.
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Protein Aliases: C1orf28; cell division cycle 73 Paf1/RNA polymerase II complex component-like protein; cell division cycle 73, Paf1/RNA polymerase II complex component, homolog; Cell division cycle protein 73 homolog; HPTJT; HRPT2; Hyperparathyroidism 2 protein; HYX; Paf1/RNA polymerase II complex component; Parafibromin
Gene Aliases: C1orf28; CDC73; FIHP; HPTJT; HRPT1; HRPT2; HYX
UniProt ID: (Human) Q6P1J9
Entrez Gene ID: (Human) 79577