The target sequence has 83% sequence homology with mouse ChREBP.
ChREBP is a transcription factor involved in activating genes that encode enzymes of fatty acid biosynthesis in liver and adipose. This protein may have relevance to lipid metabolism, obesity, and type II diabetes.
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Protein Aliases: bHLHd14; carbohydrate response element binding protein; Carbohydrate-responsive element-binding protein; CHREBP; Class D basic helix-loop-helix protein 14; MIO; MLX interacting protein-like; MLX interacting protein-like beta; MLX interactor; MLX-interacting protein-like; MONDOB; putative hepatic transcription factor; WBSCR14; Williams Beuren syndrome chromosome region 14; Williams-Beuren syndrome chromosomal region 14 protein; Williams-Beuren syndrome chromosomal region 14 protein homolog; Williams-Beuren syndrome chromosome region 14 homolog; Williams-Beuren syndrome chromosome region 14 protein 1; Williams-Beuren syndrome chromosome region 14 protein 2; Williams-Beuren syndrome chromosome region 14 protein 3; WS basic-helix-loop-helix leucine zipper protein; WS-bHLH
Gene Aliases: BHLHD14; CHREBP; MIO; MLXIPL; MONDOB; WBSCR14; WS-bHLH