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Fabgennix
Chimaerin beta 2 Polyclonal Antibody
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Product Details
CHIM-201AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 150-180 on beta 2-chimaerin protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta chimaerin; beta chimerin; Beta-chimaerin; Beta-chimerin; beta3-chimaerin; chimerin (chimaerin) 2; chimerin, beta-2; chimerin, testis-specific; OTTHUMP00000202260; Rho GTPase-activating protein 3; rho-GTPase-activating protein 3
Gene Aliases: 1700026N20Rik; 4930557O16Rik; ARHGAP3; BCH; CHN2; CHN2-3; RHOGAP3
UniProt ID: (Human) P52757, (Rat) Q03070, (Mouse) Q80XD1
Entrez Gene ID: (Human) 1124, (Rat) 84031, (Mouse) 69993
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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