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Bioss
Chrm3 Polyclonal Antibody
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Product Details
BS-1289R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from mouse Chrm3, amino acids 481-589.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor; acetylcholine receptor, muscarinic 3; AChR M3; cholinergic receptor; cholinergic receptor, muscarinic 3; cholinergic receptor, muscarinic 3, cardiac; m3 muscarinic receptor; Mm3 mAChR; muscarinic acetylcholine receptor 3; Muscarinic acetylcholine receptor M3
Gene Aliases: Chrm-3; CHRM3; EGBRS; HM3; M3; M3R; PBS
UniProt ID: (Human) P20309, (Mouse) Q9ERZ3, (Rat) P08483
Entrez Gene ID: (Human) 1131, (Mouse) 12671, (Rat) 24260
regulation of vascular smooth muscle contraction
cellular protein modification process
smooth muscle contraction
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
G-protein coupled acetylcholine receptor signaling pathway
synaptic transmission, cholinergic
nervous system development
cell proliferation
positive regulation of smooth muscle contraction
saliva secretion
chemical synaptic transmission
digestion
sensory perception of chemical stimulus
regulation of vasoconstriction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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