Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:400-1:1,600 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Chromogranin A Fusion Protein Ag0807 (158-457 aa encoded by BC006459) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.25 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MQESKAEGN NQAPGEEEEE EEEATNTHPP ASLPSQKYPG PQAEGDSEGL SQGLVDREKG LSAEPGWQAK REEEEEEEEE AEAGEEAVPE EEGPTVVLNP HPSLGYKEIR KGESRSEALA VDGAGKPGAE EAQDPEGKGE QEHSQQKEEE EEMAVVPQGL FRGGKSGELE QEEERLSKEW EDSKRWSKMD QLAKELTAEK RLEGQEEEED NRDSSMKLSF RARAYGFRGP GPQLRRGWRP SSREDSLEAG LPLQVRGYPE EKKEEEGSAN RRPEDQELES LSAIEAELEK VAHQLQALRR G (158-457 aa encoded by BC006459)
Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AL-11; AL26; Beta-granin; betagranin (N-terminal fragment of chromogranin A); Catestatin; CgA; chromofungin; Chromogranin-A; CTNNB; DKFZp686D02253; EA-92; ER-37; ES-43; FLJ25606; FLJ37923; GE-25; GR-44; GV-19; LF-19; MGC105435; p-Glu serpinin precursor; Pancreastatin; parathyroid secretory protein 1; Pituitary secretory protein I; Serpinin; Serpinin-RRG; SL21; SP-I; SS-18; Vasostatin I; Vasostatin II; Vasostatin-1; Vasostatin-2; WA-8; WE-14
Gene Aliases: CGA; CHGA; ChrA
UniProt ID: (Human) P10645, (Mouse) P26339
Entrez Gene ID: (Human) 1113, (Rat) 24258, (Mouse) 12652
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support
