Immunogen sequence: QLSAAVTALN SESNFARAYA QGISRTKYWE LIYEDSMDLI AKLPCVAAKI YRNLYREGSG IGAIDSNLDW SHNFTNMLGY TDHQFTELTR LYLTIHSDHE GGNVSAHTSH LVGSALSDPY LSFAAAMNGL AGPLHGLANQ EVLVWLTQLQ KEVGKDVSDE KLRDYIWNTL NSGRVVPGYG HAVLRKTDPR YTCQREFALK HLPNDPMFKL VAQLYKIVPN VLLEQGKAKN PWPNVDAHSG VLLQYYGMTE MNYYTVLFGV SRALGVLAQL IWSRALGFPL ERPKSMSTEG LMKFVDSKSG; Positive Samples: 22Rv1, Jurkat, 293T, HepG2, MCF7, HeLa, Mouse heart, Mouse liver, Rat testis; Cellular Location: Mitochondrion matrix
The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metabolism. This protein is nuclear encoded and transported into the mitochondrial matrix, where the mature form is found.
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Protein Aliases: Citrate (Si)-synthase; Citrate synthase, mitochondrial
Gene Aliases: 2610511A05Rik; 9030605P22Rik; Ahl4; BB234005; Cis; CS