|ELISA (ELISA)||Assay dependent.|
|Immunohistochemistry (Frozen) (IHC (F))||Assay dependent.|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Purified native collagen type II.|
|Storage buffer||whole serum|
|Storage conditions||4° C|
Reconstitute with 1 ml of distilled water and add preservative if preferred.
Type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-1 type II collagen; arthroophthalmopathy, progressive (Stickler syndrome); cartilage collagen; chondrocalcin; Collagen alpha-1(II) chain; collagen II, alpha-1 polypeptide; collagen, type II, alpha 1
Gene Aliases: ANFH; AOM; COL11A3; COL2A1; SEDC; STL1
UniProt ID: (Human) P02458
Entrez Gene ID: (Human) 1280
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