PA1-28534 detects Collagen IV from bovine, human, and mammal samples.
PA1-28534 has been successfully used in ELISA, immunohistochemistry (paraffin), immunoprecipitation, and Western applications.
The PA1-28534 immunogen is: Collagen Type IV from human and bovine placenta
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Collagen IV is a major constituent of the basement membranes along with laminins and enactins. Collagen IV is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio. Collagen IV can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha 1 type IV collagen; alpha-2 collagen type IV; alpha1(IV) collagen; Arresten; Canstatin; COL4A1 NC1 domain; Collagen alpha-1(IV) chain; Collagen alpha-2(IV) chain; collagen IV, alpha-1 polypeptide; collagen of basement membrane, alpha-1 chain; collagen, type IV, alpha 1; Del(8)Bru44H; procollagen, type IV, alpha 1; procollagen, type IV, alpha 2; retinal anterior wiring
Gene Aliases: BOS_12713; Bru; BSVD; Col4a-1; Col4a-2; COL4A1; COL4A2; Del(8)44H; ICH; POREN2; RATOR; Raw; Svc