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Invitrogen

Complement C3a Polyclonal Antibody

View all (14) Complement C3a antibodies

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Complement C3a Polyclonal Antibody

Product Details

PA1-9567

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000-1:10,000
-

ELISA (ELISA)

1:2,000-1:10,000
-
Product Specifications

Species Reactivity

Mouse

Host/Isotype

Chicken / IgY

Class

Polyclonal

Type

Antibody

Immunogen

Mouse C3 complement protein aa 678-692, part of C3a.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2066624

Product Specific Information

PA1-9567 detects C3 alpha complement in mouse samples. This product may cross react with C3a from other mammalian species.

PA1-9567 has been successfully used in Immunoblot and ELISA procedures. PA1-9567 binds to a strong band at about 9kDa (C3a), two weaker bands with one at about 115 kDa (C3 alpha) and the other at 25-36 kDa (unknown or partial C3 cleavage).

PA1-9567 immunogen is mouse C3 complement protein aa 678-692, part of C3a.

Store at 4°C for 1-2 weeks, and -20°C for long-term storage.

Target Information

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: acylation stimulating protein; C3r1; complement 3; complement component 3d; complement component C3 precursor; complement factor 3; preprocomplement component C3

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Gene Aliases: ASP; HSE-MSF; Plp

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UniProt ID: (Mouse) P01027

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Entrez Gene ID: (Mouse) 12266

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Function(s)
antigen binding endopeptidase inhibitor activity protein binding chemokine activity lipid binding C5L2 anaphylatoxin chemotactic receptor binding receptor agonist activity
Process(es)
positive regulation of type IIa hypersensitivity complement activation, lectin pathway activation of membrane attack complex positive regulation of protein phosphorylation positive regulation of activation of membrane attack complex complement receptor mediated signaling pathway proteolysis inflammatory response complement activation complement activation, alternative pathway complement activation, classical pathway opsonization response to bacterium positive regulation of vascular endothelial growth factor production positive regulation of glucose transport regulation of triglyceride biosynthetic process positive regulation of lipid storage neuron remodeling regulation of complement activation regulation of complement activation, alternative pathway leukocyte chemotaxis killing of cells of other organism oviduct epithelium development vascular smooth muscle cell differentiation B cell activation positive regulation of G-protein coupled receptor protein signaling pathway positive regulation of angiogenesis positive regulation of receptor-mediated endocytosis positive regulation of developmental growth positive regulation of phagocytosis protein maturation retina development in camera-type eye positive regulation of phagocytosis, engulfment positive regulation of ERK1 and ERK2 cascade positive regulation of glomerular mesangial cell proliferation beta-amyloid clearance complement-dependent cytotoxicity complement-mediated synapse pruning vertebrate eye-specific patterning complement activation, GZMK pathway positive regulation of opsonization positive regulation of sensory perception of pain negative regulation of vascular smooth muscle contraction positive regulation of apoptotic cell clearance
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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