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Invitrogen
Complement C3c Polyclonal Antibody, FITC
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Product Details
PA1-29718
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Cat,
Guinea pig,
Goat,
Human,
Mink,
Mouse,
Sheep,
Pig,
Rat
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C3c Complement isolated from complement-activated human serum.
Conjugate
FITC
FITC
FITC
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
Conc. Not Determined
Purification
IgG fraction
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
There is a suggested incubation period of 30-60 minutes at room temperature.
Target Information
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acylation stimulating protein; acylation-stimulating protein cleavage product; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3 convertase cleavage product; C3a anaphylatoxin; complement 3; complement C3 protein (GPC3) precursor; complement component 3; complement component 3d; complement component C3; complement component C3 precursor; complement component C3a; complement component C3b; complement component C3d; complement factor 3; epididymis secretory sperm binding protein Li 62p; prepro-C3; preprocomplement component C3; unnamed protein product
Gene Aliases: AHUS5; ARMD9; ASP; C3; C3a; C3b; C3d; CPAMD1; HEL-S-62p; HSE-MSF; Plp
UniProt ID: (Mouse) P01027, (Rat) P01026, (Guinea pig) P12387, (Human) P01024, (Bovine) Q2UVX4, (Pig) P01025
positive regulation of type IIa hypersensitivity
complement activation, lectin pathway
activation of membrane attack complex
positive regulation of protein phosphorylation
positive regulation of activation of membrane attack complex
complement receptor mediated signaling pathway
proteolysis
inflammatory response
complement activation
complement activation, alternative pathway
complement activation, classical pathway
opsonization
response to bacterium
positive regulation of vascular endothelial growth factor production
positive regulation of glucose transport
regulation of triglyceride biosynthetic process
positive regulation of lipid storage
neuron remodeling
regulation of complement activation
regulation of complement activation, alternative pathway
leukocyte chemotaxis
killing of cells of other organism
oviduct epithelium development
vascular smooth muscle cell differentiation
B cell activation
positive regulation of G-protein coupled receptor protein signaling pathway
positive regulation of angiogenesis
positive regulation of receptor-mediated endocytosis
positive regulation of developmental growth
positive regulation of phagocytosis
protein maturation
retina development in camera-type eye
positive regulation of phagocytosis, engulfment
positive regulation of ERK1 and ERK2 cascade
positive regulation of glomerular mesangial cell proliferation
beta-amyloid clearance
complement-dependent cytotoxicity
complement-mediated synapse pruning
vertebrate eye-specific patterning
complement activation, GZMK pathway
positive regulation of opsonization
positive regulation of sensory perception of pain
negative regulation of vascular smooth muscle contraction
positive regulation of apoptotic cell clearance
tolerance induction
response to xenobiotic stimulus
response to magnesium ion
response to estradiol
response to progesterone
response to estrogen
innate immune response
response to glucocorticoid
innervation
immune response
signal transduction
G-protein coupled receptor signaling pathway
positive regulation of immune response
response to other organism
fatty acid metabolic process
negative regulation of endopeptidase activity
cell surface receptor signaling pathway involved in cell-cell signaling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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