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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Complement C3c Antibodies

          Invitrogen

          Complement C3c Polyclonal Antibody, FITC

          2 References
          View all (6) Complement C3c antibodies

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          Cite Complement C3c Polyclonal Antibody, FITC

          Complement C3c Polyclonal Antibody, FITC

          Product Details

          PA1-29718

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (IHC)

          -
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:75-1:100
          -

          Immunocytochemistry (ICC/IF)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Bovine, Dog, Cat, Guinea pig, Goat, Human, Mink, Mouse, Sheep, Pig, Rat

          Published species

          Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          C3c Complement isolated from complement-activated human serum.
          View immunogen

          Conjugate

          FITC FITC FITC

          Excitation/Emission Max

          498/517 nm View spectra spectra

          Form

          Liquid

          Concentration

          Conc. Not Determined

          Purification

          IgG fraction

          Storage buffer

          PBS

          Contains

          0.09% sodium azide

          Storage conditions

          4°C, store in dark

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2274965

          Product Specific Information

          There is a suggested incubation period of 30-60 minutes at room temperature.

          Target Information

          Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: acylation-stimulating protein cleavage product; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a anaphylatoxin; Complement C3; complement C3 protein (GPC3) precursor; complement component 3; complement component 3d; complement component C3; complement component C3a; complement component C3b; complement component C3d; epididymis secretory sperm binding protein Li 62p; HSE-MSF; prepro-C3

          View more View less

          Gene Aliases: AHUS5; AI255234; ARMD9; ASP; C3; C3a; C3b; C3d; CPAMD1; HEL-S-62p; HSE-MSF; Plp

          View more View less

          UniProt ID: (Guinea pig) P12387, (Rat) P01026, (Human) P01024, (Mouse) P01027, (Bovine) Q2UVX4, (Pig) P01025

          View more View less

          Entrez Gene ID: (Guinea pig) 100135462, (Dog) 476728, (Goat) 100860826, (Rat) 24232, (Human) 718, (Mouse) 12266, (Bovine) 280677, (Pig) 397072, (Sheep) 101108131

          View more View less

          Function(s)
          endopeptidase inhibitor activity protein binding lipid binding C5L2 anaphylatoxin chemotactic receptor binding cofactor binding serine-type endopeptidase activity receptor binding protease inhibitor
          Process(es)
          positive regulation of type IIa hypersensitivity positive regulation of protein phosphorylation positive regulation of activation of membrane attack complex tolerance induction fatty acid metabolic process chemotaxis inflammatory response complement activation complement activation, alternative pathway complement activation, classical pathway blood coagulation positive regulation of vascular endothelial growth factor production positive regulation of glucose transport regulation of triglyceride biosynthetic process positive regulation of lipid storage negative regulation of endopeptidase activity response to magnesium ion response to estradiol response to progesterone response to estrogen positive regulation of G-protein coupled receptor protein signaling pathway positive regulation of angiogenesis positive regulation of developmental growth positive regulation of phagocytosis response to glucocorticoid positive regulation of ERK1 and ERK2 cascade positive regulation of apoptotic cell clearance proteolysis immune response signal transduction G-protein coupled receptor signaling pathway regulation of complement activation regulation of immune response response to bacterium neuron remodeling positive regulation of receptor-mediated endocytosis positive regulation of phagocytosis, engulfment beta-amyloid clearance complement-dependent cytotoxicity complement-mediated synapse pruning vertebrate eye-specific patterning cell surface receptor signaling pathway involved in cell-cell signaling innate immune response
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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