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Invitrogen
Complement C3c Polyclonal Antibody, FITC
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Product Details
PA1-29718
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Cat,
Guinea pig,
Goat,
Human,
Mink,
Mouse,
Sheep,
Pig,
Rat
Published species
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C3c Complement isolated from complement-activated human serum.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
Conc. Not Determined
Purification
IgG fraction
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
There is a suggested incubation period of 30-60 minutes at room temperature.
Target Information
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acylation-stimulating protein cleavage product; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a anaphylatoxin; Complement C3; complement C3 protein (GPC3) precursor; complement component 3; complement component 3d; complement component C3; complement component C3a; complement component C3b; complement component C3d; epididymis secretory sperm binding protein Li 62p; HSE-MSF; prepro-C3; unnamed protein product
Gene Aliases: AHUS5; AI255234; ARMD9; ASP; C3; C3a; C3b; C3d; CPAMD1; HEL-S-62p; HSE-MSF; Plp
UniProt ID: (Guinea pig) P12387, (Human) P01024, (Rat) P01026, (Mouse) P01027, (Bovine) Q2UVX4, (Pig) P01025
positive regulation of type IIa hypersensitivity
complement activation, lectin pathway
activation of membrane attack complex
positive regulation of protein phosphorylation
positive regulation of activation of membrane attack complex
immune system process
complement receptor mediated signaling pathway
lipid metabolic process
fatty acid metabolic process
inflammatory response
immune response
complement activation
complement activation, alternative pathway
complement activation, classical pathway
signal transduction
G-protein coupled receptor signaling pathway
opsonization
response to bacterium
positive regulation of vascular endothelial growth factor production
positive regulation of glucose transport
regulation of triglyceride biosynthetic process
positive regulation of lipid storage
neuron remodeling
leukocyte chemotaxis
killing of cells of other organism
oviduct epithelium development
B cell activation
innate immune response
positive regulation of G-protein coupled receptor protein signaling pathway
positive regulation of angiogenesis
positive regulation of receptor-mediated endocytosis
positive regulation of phagocytosis
protein maturation
positive regulation of phagocytosis, engulfment
beta-amyloid clearance
complement-dependent cytotoxicity
complement-mediated synapse pruning
vertebrate eye-specific patterning
complement activation, GZMK pathway
positive regulation of apoptotic cell clearance
tolerance induction
chemotaxis
blood coagulation
negative regulation of endopeptidase activity
response to magnesium ion
response to estradiol
response to progesterone
response to estrogen
positive regulation of developmental growth
response to glucocorticoid
positive regulation of ERK1 and ERK2 cascade
cell surface receptor signaling pathway involved in cell-cell signaling
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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