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Invitrogen
Complement C4a Polyclonal Antibody
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FIGURE: 1 / 1
Complement C4a Antibody (PA5-109468) in WB
Western blot analysis of Complement C4 in extracts of HepG2 cells. Samples were incubated with Complement C4 Polyclonal antibody (Product # PA5-109468) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-109468
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1446 of human Complement C4A (NP_0092242)
Conjugate
Form
Liquid
Concentration
1.14 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LTLTKAPVDL LGVAHNNLMA MAQETGDNLY WGSVTGSQSN AVSPTPAPRN PSDPMPQAPA LWIETTAYAL LHLLLHEGKA EMADQASAWL TRQGSFQGGF RSTQDTVIAL DALSAYWIAS HTTEERGLNV TLSSTGRNGF KSHALQLNNR QIRGLEEELQ FSLGSKINVK VGGNSKGTLK VLRTYNVLDM KNTTCQDLQI EVTVKGHVEY TMEANEDYED YEYDELPAKD DPDAPLQPVT PLQLFEG
Target Information
Complement C4a is a protein that is part of the complement system, which is a group of proteins that work together to help the immune system fight off infections. C4a is produced when the complement system is activated, and it plays a role in inflammation and the recruitment of immune cells to the site of infection. It is also involved in the clearance of immune complexes and the regulation of the complement system.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acidic C4; Acidic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; c4 propeptide; C4A; C4A anaphylatoxin; C4AD; CO4A; Complement C4-A; complement C4A (Rodgers blood group); complement component 4A (Rodgers blood group); MHC class III region complement; Rodgers form of C4; unnamed protein product; ZA
Gene Aliases: C4; C4A; C4A2; C4A3; C4A4; C4A6; C4AD; C4S; CO4; CPAMD2; RG
UniProt ID: (Human) P0C0L4
Entrez Gene ID: (Human) 720
complement activation, lectin pathway
activation of membrane attack complex
immune system process
inflammatory response
complement activation
complement activation, classical pathway
opsonization
killing of cells of other organism
innate immune response
protein maturation
complement activation, GZMK pathway
positive regulation of apoptotic cell clearance
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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