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Invitrogen
Complement C6 Polyclonal Antibody
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FIGURE: 1 / 2
Complement C6 Antibody (PA5-101538) in ICC/IF
Immunocytochemistry analysis of Complement C6 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Complement C6 polyclonal antibody (Product # PA5-101538) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conj... View More
Product Details
PA5-101538
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human C6(Accession P13671), corresponding to amino acid residues K222-S272.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total C6.
Target Information
C6 is a component of complement cascade. It is part of the membrane attack complex which can insert into the cell membrane and cause cell to lyse. People with C6 deficiency are prone to bacterial infection. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Complement component C6
Gene Aliases: C6
UniProt ID: (Human) P13671, (Rat) Q811M5
Entrez Gene ID: (Human) 729, (Rat) 24237
in utero embryonic development
positive regulation of activation of membrane attack complex
complement activation
complement activation, classical pathway
cytolysis
regulation of complement activation
innate immune response
positive regulation of angiogenesis
immune response
positive regulation of apoptotic process
positive regulation of complement activation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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