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|Tested species reactivity||Human, Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide derived from the C-terminal region of the mouse, rat, golden and Chinese hamster, and predicted dog connexin 37 proteins, which differ from human and chimpanzee by two conservative amino acid changes|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:10-1:50|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:50|
|Western Blot (WB)||2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
42-4400 was used in the western blot analysis to successfully detect Connexin 37 in mouse lung homogenate.
This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Mouse||Not Cited||TIMP-2 mutant decreases MMP-2 activity and augments pressure overload induced LV dysfunction and heart failure.||Givvimani S,Kundu S,Narayanan N,Armaghan F,Qipshidze N,Pushpakumar S,Vacek TP,Tyagi SC||Archives of physiology and biochemistry (119:65)||2013|
|Mouse||Not Cited||Cx37 and Cx43 localize to zona pellucida in mouse ovarian follicles.||Simon AM,Chen H,Jackson CL||Cell communication & adhesion (13:61)||2006|
connexin 37; connexin-37; Cx37; Cxn-37; gap junction alpha-4 protein; gap junction membrane channel protein alpha 4; gap junction protein, alpha 4, 37kDa; Gja4
AU020209; AW558810; Cnx37; CX37; Cxn-37; Gja-4; GJA4