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Copeptin Antibody (710321) in WB
Western blot analysis of Vasopressin in whole cell extracts from transfected HEK293 cells using a Copeptin Recombinant Rabbit Polyclonal Antibody (Product # 710321) at a dilution of 1 µg/mL. Samples were detected using chemiluminescence (ECL). Results show a band at ~18kDa.
Product Details
710321
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Polyclonal
Type
Antibody
Clone
20HCLC
Immunogen
Peptide corresponding to amino acids 126–164 of human Copeptin
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2532688
Product Specific Information
This antibody is predicted to react with mouse, rat, non-human primate and rabbit based on sequence homology.
Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
Target Information
Copeptin is a member of vasopressin/oxytocin family. It is a 39-amino acid peptide produced from cleavage of preprovasopressin during precursor processing, and is released along with the hormone arginine vasopressin. Copeptin acts to ensure the proper structural formation of arginine vasopressin during precursor processing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antidiuretic hormone; Arg-vasopressin; Arginine-vasopressin; AVP-NPII; Copeptin; neurohypophyseal; Neurophysin 2; Neurophysin-II; prepro-arginine-vasopressin-neurophysin II; prepro-AVP-NP II; Vasopressin-neurophysin 2-copeptin; vasopressin-neurophysin II-copeptin
Gene Aliases: ADH; ARVP; AVP; AVP-NPII; AVRP; VP
UniProt ID: (Human) P01185
Entrez Gene ID: (Human) 551
Molecular Function:
neuropeptide
maternal aggressive behavior
positive regulation of systemic arterial blood pressure
renal water homeostasis
generation of precursor metabolites and energy
water transport
apoptotic process
signal transduction
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
negative regulation of female receptivity
grooming behavior
locomotory behavior
positive regulation of cell proliferation
positive regulation of gene expression
positive regulation of glutamate secretion
positive regulation of cell growth
positive regulation of cAMP biosynthetic process
positive regulation of prostaglandin biosynthetic process
positive regulation of cellular pH reduction
positive regulation of peptidyl-serine phosphorylation
response to testosterone
response to nicotine
social behavior
regulation of renal sodium excretion
vasoconstriction
hyperosmotic salinity response
maternal behavior
negative regulation of apoptotic process
penile erection
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
sodium-independent organic anion transport
response to ethanol
positive regulation of vasoconstriction
negative regulation of transmission of nerve impulse
ERK1 and ERK2 cascade
protein kinase C signaling
negative regulation of release of cytochrome c from mitochondria
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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