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Product Details
BS-7685R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Sheep,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Corin, amino acids 165-245.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. CORIN converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Atrial natriuretic peptide-converting enzyme; Corin; EC 3.4.21; Heart-specific serine proteinase ATC2; Low density lipoprotein receptor-related protein 4; low density lipoprotein-related protein 4; MGC119742; pro-ANP-convertase; Pro-ANP-converting enzyme; PRSC; serine peptidase; serine protease; Transmembrane protease serine 10
Gene Aliases: ATC2; AV273130; CORIN; CRN; Lrp4; PEE5; TMPRSS10
UniProt ID: (Human) Q9Y5Q5, (Mouse) Q9Z319, (Rat) Q80YN4
Entrez Gene ID: (Human) 10699, (Sheep) 101112571, (Mouse) 53419, (Rat) 289596
regulation of systemic arterial blood pressure by atrial natriuretic peptide
female pregnancy
regulation of blood pressure
peptide hormone processing
regulation of renal sodium excretion
regulation of cardiac conduction
proteolysis
protein processing
neuron differentiation
receptor-mediated endocytosis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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