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PA5-19684 targets Cre recombinase in Western blot applications and shows reactivity with Virus samples.
The PA5-19684 immunogen is synthetic peptide conjugated to KLH derived from within residues 250 to the C-terminus of Bacteriophage P1 Cre recombinase.
PA5-19684 detects Cre recombinase which has a predicted molecular weight of approximately 38 kDa.
Cre-recombinase is a 38 kDa DNA recombinase derived from the P1 bacteriophage. It is highly specific for a 34 bp DNA sequence (loxP) found in P1 DNA. It catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state. It is homotetramer when bound to DNA and belongs to the "phage" integrase family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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