Bioss

Cux2 Polyclonal Antibody

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Cux2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti Cux2 Polyclonal Antibody, Unconjugated (bs-11832R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

Cux2 Antibody in Immunofluorescence (IF) — Paraformaldehyde-fixed, paraffin embedded Mouse eye; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with Cux2 Polyclonal Antibody, Unconjugated (bs-11832R) at 1:100 overnight at 4°C, followed by a conjugated Goat Anti-Rabbit IgG antibody (bs-0295G-FITC) for 90 minutes, and DAPI for nuclei staining.

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Immunofluorescence (IF)

1:100

Product Specifications

Species Reactivity

Rat, Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Cux2.

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 50% glycerol, 1% BSA

Contains

0.09% sodium azide

Storage conditions

-20°C

Target Information

CUX2 may be a transcription factor involved in neural specification. It binds to DNA in a sequence-specific manner.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: cut-like 2; cut-like homeobox 2; Homeobox protein cut-like 2; Homeobox protein Cux-2

Gene Aliases: 1700051K22Rik; CDP2; CUTL2; Cux-2; CUX2; ENSMUSG00000072641; KIAA0293

UniProt ID: (Human) O14529, (Mouse) P70298

Entrez Gene ID: (Human) 23316, (Rat) 288665, (Mouse) 13048

Molecular Function: helix-turn-helix transcription factor homeobox transcription factor nucleic acid binding transcription factor

Function(s)

negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated short-term memory positive regulation of gene expression positive regulation of dendrite morphogenesis cognition positive regulation of synapse assembly positive regulation of dendritic spine morphogenesis cellular response to organic substance positive regulation of excitatory postsynaptic potential transcription from RNA polymerase II promoter negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated

Process(es)

RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding sequence-specific DNA binding DNA binding

Cux2 Polyclonal Antibody

Product Details

Target Information

References (0)

Bioinformatics

Material safety data sheets (MSDS)

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