Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:3,000 | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:10-1:100 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Cyclin B2 Fusion Protein Ag16329 (1-243 aa encoded by BC105086) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.33 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MALLRRPTV SSDLENIDTG VNSKVKSHVT IRRTVLEEIG NRVTTRAAQV AKKAQNTKVP VQPTKTTNVN KQLKPTASVK PVQMEKLAPK GPSPTPEDVS MKEENLCQAF SDALLCKIED IDNEDWENPQ LCSDYVKDIY QYLRQLEVLQ SINPHFLDGR DINGRMRAIL VDWLVQVHSK FRLLQETLYM CVGIMDRFLQ VQPVSRKKLQ LVGITALLLA SKYEEMFSPN IEDFVYITDN AYTS (1-243 aa encoded by BC105086)
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G2/mitotic-specific cyclin B2; G2/mitotic-specific cyclin-B2
Gene Aliases: CCNB2; CycB2; HsT17299
UniProt ID: (Human) O95067, (Mouse) P30276
Entrez Gene ID: (Human) 9133, (Rat) 363088, (Mouse) 12442
Molecular Function:
kinase activator
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