Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 7 publications 7 publications |
Immunohistochemistry (IHC) |
- | View 5 publications 5 publications |
Immunocytochemistry (ICC/IF) |
- | View 1 publication 1 publication |
Miscellaneous PubMed (Misc) |
- | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Published species |
Human, Mouse, Pig |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Cyclin D2 Fusion Protein Ag1377 (1-289 aa encoded by BC010958) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.3 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MELLCHEVD PVRRAVRDRN LLRDDRVLQN LLTIEERYLP QCSYFKCVQK DIQPYMRRMV ATWMLEVCEE QKCEEEVFPL AMNYLDRFLA GVPTPKSHLQ LLGAVCMFLA SKLKETSPLT AEKLCIYTDN SIKPQELLEW ELVVLGKLKW NLAAVTPHDF IEHILRKLPQ QREKLSLIRK HAQTFIALCA TDFKFAMYPP SMIATGSVGA AICGLQQDEE VSSLTCDALT ELLAKITNTD VDCLKACQEQ IEAVLLNSLQ QYRQDQRDGS KSEDELDQAS TPTDVRDIDL (1-289 aa encoded by BC010958)
Cyclin D2 is a G1 cyclin required for G1 phase progression and is a strong candidate for a proto-oncogene. Cyclin D2 can phosphorylate pRB when associated with cdk 4 and / or cdk 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G1/S-specific cyclin-D2; MGC102758
Gene Aliases: 2600016F06Rik; AI256817; BF642806; C86853; CCND2; cD2; Cyl-2; KIAK0002; MPPH3; Vin-1; Vin1
UniProt ID: (Human) P30279, (Mouse) P30280
Entrez Gene ID: (Human) 894, (Mouse) 12444
Molecular Function:
kinase activator
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