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Cyclin D2 Polyclonal Antibody
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FIGURE: 1 / 4
Cyclin D2 Antibody (BS-1148R) in ICC/IF
Image provided by One World Lab validation program. A431 cells probed with Rabbit Anti-Cyclin D2 Polyclonal Antibody (bs-1148R) at 1:200 for 60 minutes at room temperature followed by Goat Anti-Rabbit IgG (H+L) Alexa Fluor 488 Conjugated secondary antibody.
Product Details
BS-1148R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Cyclin D2, amino acids 161-288.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Cyclin D2 is a G1 cyclin required for G1 phase progression and is a strong candidate for a proto-oncogene. Cyclin D2 can phosphorylate pRB when associated with cdk 4 and / or cdk 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G1/S-specific cyclin-D2; KIAK0002; MGC102758; unnamed protein product; Vin-1 proto-oncogene
Gene Aliases: 2600016F06Rik; AI256817; BF642806; C86853; CCND2; cD2; Cyl-2; KIAK0002; MPPH3; Vin-1; Vin1
UniProt ID: (Human) P30279, (Rat) Q04827, (Mouse) P30280
Entrez Gene ID: (Human) 894, (Rat) 64033, (Mouse) 12444
G1/S transition of mitotic cell cycle
long-term memory
positive regulation of cell proliferation
adult locomotory behavior
negative regulation of apoptotic process
cell division
regulation of cell cycle
cellular response to X-ray
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of mitotic cell cycle phase transition
regulation of G1/S transition of mitotic cell cycle
ovarian follicle development
liver development
positive regulation of protein phosphorylation
spermatogenesis
response to organic cyclic compound
response to estradiol
cellular response to insulin stimulus
response to testosterone
response to peptide hormone
response to ethanol
regulation of neuron differentiation
positive regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of epithelial cell proliferation
response to cAMP
cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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