Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign In
Don't have an account ? Create Account
  • Applications
    • Real-Time PCR
    • Oligos, Primers, Probes and Genes
    • Cloning
    • Protein Biology
    • Cell Culture and Transfection
    • Cell and Gene Therapy
    • Cell Analysis
    • Mass Spectrometry
    • Chromatography
    • Spectroscopy, Elemental and Isotope Analysis
    • See all applications and techniques
  • Online Order
    • Custom Primers & TaqMan Probes
    • miRNA Mimics & Inhibitors
    • Stealth RNAi / siRNA
    • Silencer Select siRNAs
    • Custom DNA Oligos
    • GeneArt Services
    • GeneArt Strings DNA Fragments
    • TrueGuide CRISPR gRNA
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • See all online orderable products
  • Services
    • Custom Services
    • Instrument Qualification Services
    • Technical Services
    • Enterprise Services
    • Pipette Services
    • Sample Request
    • Instrument Maintenance Services
    • Repairs and Relocation Services
    • OEM and Licensing Services
    • Events, Seminars, Training
    • See all services
  • Support
    • Catalogs
    • Application Notes
    • Safety Data Sheets
    • Legal and Regulatory
    • Certificates of Analysis Search
    • Nunc/Nalgene Product Certificates
    • e-learning
    • FAQs
    • Learning Centers
    • Technical Support Centers
    • See all help and support topics
  • Contact Us
  • Quick Order
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search

Search All
Search button
          • Contact Us
          • Quick Order
          • Sign In
            Sign In
            Don't have an account ? Create Account
            • Connect Your Lab
            • Custom Products & Projects
            • Instrument Management

          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • DRD2 Antibodies

          Fabgennix

          D2 Receptor Polyclonal Antibody, FITC

          View all (26) DRD2 antibodies

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Protocols
          Questions & Answers
          Tech Support

          Cite D2 Receptor Polyclonal Antibody, FITC

          D2 Receptor Polyclonal Antibody, FITC

          Product Details

          D2R-FITC

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (IHC)

          1:50-1:250
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:250
          -

          ELISA (ELISA)

          1:10,000
          -

          Immunoprecipitation (IP)

          1:50-1:250
          -

          Immunomicroscopy (IM)

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide taken within amino acid region 150-200 on rat Dopamine Receptor D2 protein.
          View immunogen

          Conjugate

          FITC FITC FITC

          Excitation/Emission Max

          498/517 nm View spectra spectra

          Form

          Liquid

          Concentration

          0.5-1.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinsons disease. Three alternatively spliced isoforms have been identified. DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: D(2) dopamine receptor; D2 receptor; Dopamine 2 receptor; Dopamine D2 receptor; dopamine receptor 2

          View more View less

          Gene Aliases: D2R; Drd-2; Drd2

          View more View less

          UniProt ID: (Mouse) P61168, (Rat) P61169

          View more View less

          Entrez Gene ID: (Mouse) 13489, (Rat) 24318

          View more View less

          Function(s)
          dopamine neurotransmitter receptor activity, coupled via Gi/Go signal transducer activity G-protein coupled receptor activity dopamine neurotransmitter receptor activity receptor binding drug binding dopamine binding ionotropic glutamate receptor binding identical protein binding protein homodimerization activity protein heterodimerization activity protein binding G-protein coupled receptor
          Process(es)
          temperature homeostasis response to hypoxia synaptic transmission, dopaminergic startle response response to amphetamine neurological system process involved in regulation of systemic arterial blood pressure regulation of heart rate regulation of sodium ion transport G-protein coupled receptor internalization positive regulation of neuroblast proliferation positive regulation of receptor internalization signal transduction G-protein coupled receptor signaling pathway adenylate cyclase-modulating G-protein coupled receptor signaling pathway negative regulation of adenylate cyclase activity adenylate cyclase-inhibiting dopamine receptor signaling pathway dopamine receptor signaling pathway chemical synaptic transmission neuron-neuron synaptic transmission axonogenesis sensory perception of smell long-term memory grooming behavior locomotory behavior adult walking behavior feeding behavior protein localization negative regulation of cell proliferation associative learning visual learning response to light stimulus response to toxic substance regulation of dopamine secretion Wnt signaling pathway cerebral cortex GABAergic interneuron migration adenohypophysis development negative regulation of cell migration peristalsis adult behavior regulation of cAMP metabolic process forebrain development auditory behavior activation of protein kinase activity regulation of synaptic transmission, GABAergic positive regulation of cytokinesis circadian regulation of gene expression negative regulation of dopamine secretion response to histamine intracellular signal transduction positive regulation of urine volume positive regulation of renal sodium excretion positive regulation of multicellular organism growth response to cocaine negative regulation of circadian sleep/wake cycle, sleep dopamine metabolic process response to drug regulation of potassium ion transport response to morphine regulation of MAPK cascade pigmentation regulation of phosphoprotein phosphatase activity positive regulation of G-protein coupled receptor protein signaling pathway negative regulation of blood pressure positive regulation of transcription from RNA polymerase II promoter phosphatidylinositol metabolic process negative regulation of insulin secretion acid secretion behavioral response to cocaine behavioral response to ethanol regulation of long-term neuronal synaptic plasticity branching morphogenesis of a nerve arachidonic acid secretion negative regulation of protein secretion modulation of synaptic transmission release of sequestered calcium ion into cytosol negative regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway regulation of dopamine uptake involved in synaptic transmission positive regulation of dopamine uptake involved in synaptic transmission regulation of synapse structural plasticity negative regulation of protein kinase B signaling negative regulation of synaptic transmission, glutamatergic positive regulation of growth hormone secretion prepulse inhibition phospholipase C-activating dopamine receptor signaling pathway negative regulation of dopamine receptor signaling pathway positive regulation of ERK1 and ERK2 cascade regulation of locomotion involved in locomotory behavior positive regulation of glial cell-derived neurotrophic factor secretion positive regulation of long-term synaptic potentiation negative regulation of voltage-gated calcium channel activity synapse assembly response to iron ion response to inactivity striatum development orbitofrontal cortex development cellular potassium ion homeostasis response to nicotine response to ethanol positive regulation of mitotic nuclear division response to axon injury
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          Ordering Plus Icon Minus Icon
          • Online Orderable Products
          • Privacy Policy for Online Ordering
          • Act on Specified Commercial Transactions
          • About Returns
          • About Displayed Prices
          • About Shipping Fees
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us
          • Technical Support Centers
          • Documents and Certificates
          • Study information disclosure
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Seminars
          • Blog
          About Thermo Fisher Plus Icon Minus Icon
          • Corporate Information
          • Social Responsibility (CSR)
          • Enhancing Customer Experience
          • Careers Careers
          • News
          • Trademarks
          • Policies and Notices
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Unity Lab Services
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Policy
          © 2006-2026 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          Japan flag icon
          Japan

          Your items have has been added!


          Host server : magellan-search-green-55658555d6-c46gj:80/100.66.76.55:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline