Invitrogen

D4-GDI Polyclonal Antibody

View all (17) D4-GDI antibodies

Questions & Answers

Questions & Answers

Product Image Gallery

D4-GDI Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of D4-GDI in human bone marrow tissue using D4-GDI Polyclonal Antibody (Product # PA5-111332). Staining shows strong cytoplasmic and nuclear positivity in hematopoietic cells.

D4-GDI Antibody in Western Blot (WB) — Western blot analysis of D4-GDI in Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10, Lane 2: Human cell line RT-4, Lane 3: Human cell line U-251MG sp, Lane 4: Human plasma (IgG/HSA depleted), Lane 5: Human liver tissue, Lane 6: Human tonsil tissue using D4-GDI Polyclonal Antibody (Product # PA5-111332).

Product Details

PA5-111332

Applications	Tested Dilution	Publications
Western Blot (WB)	0.04-0.4 µg/mL	-
Immunohistochemistry (IHC)	1:200-1:500	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Recombinant Protein corresonding to Human D4-GDI View antigen
Conjugate	Unconjugated
Form	Liquid
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.2, with 40% glycerol
Contains	0.02% sodium azide
Storage conditions	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID	AB_2856742

Product Specific Information

Immunogen sequence: PEPHVEEDDD DELDSKLNYK PPPQKSLKEL QEMDKDDE

Target Information

Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?

Let us know so we can reference it here.

Cite this product

Bioinformatics

Protein Aliases: d4 gdi; GDI LYGDI; Ly-GDI; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP-dissociation inhibitor 2; Rho-GDI beta

Gene Aliases: ARHGDIB; D4; GDIA2; GDID4; Ly-GDI; LYGDI; RAP1GN1; RhoGDI2

UniProt ID: (Human) P52566

Entrez Gene ID: (Human) 397

Molecular Function: G-protein modulator

movement of cell or subcellular component negative regulation of cell adhesion multicellular organism development regulation of Rho protein signal transduction positive regulation of GTPase activity regulation of small GTPase mediated signal transduction cellular response to redox state negative regulation of trophoblast cell migration regulation of actin cytoskeleton reorganization

Process(es)

GTPase activity Rho GDP-dissociation inhibitor activity GTPase activator activity protein binding Rac GTPase binding