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PA5-16781 targets D4-GDI in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-16781 immunogen is recombinant full-length human D4-GDI protein.
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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