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Immunogen sequence: VRRIKMATA DEIVKLMLDH MTNTTNASHV PVQPGSSVVM MVNNLGGLSF LELGIIADAT VRSLEGRGVK IARALVGTFM SALEMPGISL TLLLVDEPLL KLIDAETTAA AWPNVAAVSI TGRKRSRVAP AEPQEAPDST AAGGSASKRM ALVLERVCST LLGLEEHLNA LDRAAGDGDC GTTHSRAARA IQEWLKEGPP PASPAQLLSK LSVLLLEKMG GSSGALYGLF LTAAAQPLKA KTSLPAWSAA MDAGLEAMQK YGKAAPGDRT MLDSLWAAGQ ELQAWKSPGA DLLQVLTKAV KSAEAAAEAT KNMEAGAGRA SYISSARLEQ PDPGAVAAAA ILRAILEVLQ S (226-576 aa encoded by BC001341)
This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4',5'-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been identified, but the full-length nature of only one has been determined.
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Protein Aliases: ATP-dependent dihydroxyacetone kinase; Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); DHA kinase; Dha kinase/FMN cyclase; dihydroxyacetone kinase 2 homolog; DKFZP586B1621; FAD-AMP lyase (cyclic FMN forming); FAD-AMP lyase (cyclizing); FAD-AMP lyase cyclic FMN forming; FAD-AMP lyase cyclizing; FMN cyclase; Glycerone kinase; MGC5621; testis tissue sperm-binding protein Li 84P; Triokinase; Triokinase/FMN cyclase; Triose kinase
Gene Aliases: BC021917; DAK; NET45; RGD1311026; TKFC
Molecular Function: cyclase