Proteintech

DBR1 Polyclonal Antibody

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DBR1 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of Hela cells, using DBR1 antibody 16019-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

DBR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human placenta using 16019-1-AP (DBR1 antibody) at dilution of 1:100 (under 40x lens).

DBR1 Antibody in Western Blot (WB) — Human brain tissue were subjected to SDS PAGE followed by western blot with 16019-1-AP (DBR1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

16019-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:3,000	View 4 publications 4 publications
Immunohistochemistry (IHC)	-	View 1 publication 1 publication
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	1:10-1:100	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	DBR1 Fusion Protein Ag8830 (204-544 aa encoded by BC009472) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.37 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: TLGSPAASE LLEHLKPTYW FSAHLHVKFA ALMQHQAKDK GQTARATKFL ALDKCLPHRD FLQILEIEHD PSAPDYLEYD IEWLTILRAT DDLINVTGRL WNMPENNGLH ARWDYSATEE GMKEVLEKLN HDLKVPCNFS VTAACYDPSK PQTQMQLIHR INPQTTEFCA QLGIIDINVR LQKSKEEHHV CGEYEEQDDV ESNDSGEDQS EYNTDTSALS SINPDEIMLD EEEDEDSIVS AHSGMNTPSV EPSDQASEFS ASFSDVRILP GSMIVSSDDT VDSTIDREGK PGGTVESGNG EDLTKVPLKR LSDEHEPEQR KKIKRRNQAI YAAVDDDDDD AA (204-544 aa encoded by BC009472)

Target Information

The RNA lariat debranching enzyme, or DBR1, specifically hydrolyzes 2-prime-to-5-prime branched phosphodiester bonds at the branch point of excised lariat intron RNA and converts them into linear molecules.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection.

Cell

Zhang SY,Clark NE,Freije CA,Pauwels E,Taggart AJ,Okada S,Mandel H,Garcia P,Ciancanelli MJ,Biran A,Lafaille FG,Tsumura M,Cobat A,Luo J,Volpi S,Zimmer B,Sakata S,Dinis A,Ohara O,Garcia Reino EJ,Dobbs K,Hasek M,Holloway SP,McCammon K,Hussong SA,DeRosa N,Van Skike CE,Katolik A,Lorenzo L,Hyodo M,Faria E,Halwani R,Fukuhara R,Smith GA,Galvan V,Damha MJ,Al-Muhsen S,Itan Y,Boeke JD,Notarangelo LD,Studer L,Kobayashi M,Diogo L,Fairbrother WG,Abel L,Rosenberg BR,Hart PJ,Etzioni A,Casanova JL